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Early phase support for plasmid DNA supply to secure future manufacturing

Drug Discovery World

billion by 2030 (BioSpace, 11 August 2022). Plasmid DNA: a critical reagent pDNA is the starting material for the development of many cell and gene therapy products, irrespective of the mode of action. This rapid emergence of cell and gene therapies has fuelled demand for plasmids and has created a manufacturing ‘bottleneck’.

DNA 130
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Advances in cell line development

Drug Discovery World

According to Grand View Research, the global cell line development market was valued at $4.81 billion in 2022, a figure that is expected to grow at a compound annual growth rate (CAGR) of 9.81% from 2023 to 2030 1. Looking ahead, it’s clear that the role of technology is playing a big role in advancing cell lines.

Vaccine 147
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The evolution of assays for immuno-oncology research

Drug Discovery World

Another revolutionary discovery was the elucidation of the role of IL2 in T cell growth and activation in the 1970s, that later paved the way for the treatment of patients with metastatic melanoma and renal cancer. Over 250 clinical trials are currently in progress, and novel immuno-oncological treatments are already proving to be successful.

Research 130