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Early phase support for plasmid DNA supply to secure future manufacturing

Drug Discovery World

pDNA is a critical raw material for advanced therapeutics including mRNA and viral vector-based cell and gene therapies and vaccines. billion by 2030 (BioSpace, 11 August 2022). coli cell lines), or later in the process using existing GMP cell banks for programs that have already completed early phase trials, for example.

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Advances in cell line development

Drug Discovery World

According to Grand View Research, the global cell line development market was valued at $4.81 billion in 2022, a figure that is expected to grow at a compound annual growth rate (CAGR) of 9.81% from 2023 to 2030 1. There are a lot of considerations to take when choosing a cell line.

Vaccine 147
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The evolution of assays for immuno-oncology research

Drug Discovery World

These have been the most promising form of antibodies being developed, with Ipilimumab (CTLA4 blocking) and Nivolumab (PD1 blocking) now approved by the US Food and Drug Administration (FDA) for more than nine cancer types. A brief history of vaccines and vaccination. Front Immunol. 2017) 8:829. doi: 10.3389/fimmu.2017.00829

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