Science Daily: Pharmacology News
JANUARY 1, 2025
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans -- including those causing flu, COVID, whooping cough and tuberculosis.
BioPharma Drive: Drug Pricing
JANUARY 2, 2025
Expected readouts in diabetes, cancer and depression headline a series of study results that could help the biotechnology sector regain its footing after a shaky year.
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Drugs.com
DECEMBER 30, 2024
MONDAY, Dec. 30, 2024 -- Norovirus, a highly contagious stomach bug, is surging across the United States this winter, according to the latest data from the U.S. Centers for Disease Control and Prevention (CDC).The data shows 91 outbreaks of.
Chemical Biology and Drug Design
DECEMBER 29, 2024
Cover Image molekuul_be/Shutterstock.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Covalent Modifiers
DECEMBER 28, 2024
Ai-Lin Chen, Zih-Jheng Lin, Hsiao-Yu Chang, and Tsung-Shing Andrew Wang Journal of the American Chemical Society , 2025 [link] Reactive carbonyl species (RCS) are important biomarkers of oxidative stress-related diseases because of their highly reactive electrophilic nature. Despite their potential as triggers for prodrug activation, selective labeling approaches for RCS remain limited.
Science Daily: Pharmacology News
JANUARY 2, 2025
Viral infections may play a role in Alzheimer's disease.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
JANUARY 2, 2025
THURSDAY, Jan. 2, 2024 -- Weight loss tops many folks list of New Years resolutions, and lots of people are turning to cutting-edge weight-loss drugs like Ozempic to help them drop excess pounds.These drugs, called glucagon-like peptide-1 receptor.
Chemical Biology and Drug Design
DECEMBER 30, 2024
Compound 8w suppressed BaF3 cells harboring CCDC6-RET V804M mutations with IC 50 values of 0.715M and dose-dependently suppressed the activation of RET and downstream signals. Another compound 8s suppressed BaF3 cells harboring CCDC6-RET G810C mutation with an IC 50 value of 2.91M. Therefore, 8w and 8s might be promising lead compounds. ABSTRACT RET (Rearranged during transfection) kinase is a validated target for non-small cell lung cancer (NSCLC).
BioPharma Drive: Drug Pricing
JANUARY 2, 2025
The well-funded biotech lost most of its value after its drug flunked a late-stage trial. One analyst described the results as a “worst-case scenario for the program.
Science Daily: Pharmacology News
JANUARY 1, 2025
Waves of human migration across Europe during the first millennium AD have been revealed using a more precise method of analysing ancestry with ancient DNA, in research led by the Francis Crick Institute.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Patent Watch
DECEMBER 30, 2024
The regulatory environment in Japan for generic drug development is complex and has undergone significant changes in recent years. This article aims to provide a comprehensive overview of the key aspects of the regulatory framework, highlighting the requirements and challenges faced by pharmaceutical companies seeking to introduce generic drugs into the Japanese market.
Drugs.com
JANUARY 3, 2025
FRIDAY, Jan. 3, 2025 -- If you've picked up a bag of Marketside Broccoli Florets from Walmart recently, check your fridge or freezer. The company has issued a recall of the 12-ounce bags in 20 states after testing uncovered listeria bacteria in one.
Covalent Modifiers
JANUARY 1, 2025
Kyosuke Shishikura, Jiasong Li, Yiming Chen, Nate R McKnight, Katelyn A Bustin, Eric W Barr, Snehil R Chilkamari, Mahaa Ayub, Sun Woo Kim, Zongtao Lin, Ren-Ming Hu, Kelly Hicks, Xie Wang, Donald M O'Rourke, J. Martin Bollinger Jr., Zev A Binder, William H Parsons, Kirill A Martemyanov, Aimin Liu, Megan L Matthews bioRxiv 2024.12.19.629450; doi: [link] The vasodilator hydralazine (HYZ) has been used clinically for ~ 70 years and remains on the World Health Organization's List of Essential Medicin
BioPharma Drive: Drug Pricing
JANUARY 2, 2025
The agency’s main drug review office cleared 50 novel medicines last year, short of 2018’s record total but on the higher end of recent annual tallies.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
JANUARY 2, 2025
Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement. This study marks an important step toward regenerative therapies to prevent heart failure.
Collaborative Drug
DECEMBER 30, 2024
2024 was a special year as we celebrated two decades of CDD Vault.
Drugs.com
JANUARY 2, 2025
THURSDAY, Jan. 2, 2025 -- Considering a New Year’s resolution to quit smoking? New research might provide all the motivation you need: Each cigarette could shorten your life by up to 22 minutes, researchers say. The findings, published Dec.
addgene Blog
JANUARY 2, 2025
Every year, we like to add in some holiday cheer to our blog and social media. This year, we're doing so through the twelve days of antibodies. We hope you enjoy it, and we wish you a great 2025!
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
JANUARY 2, 2025
Sangamo shares fell on Pfizer’s decision to hand back rights to a hemophilia gene therapy. Elsewhere, Novartis got long-awaited data and BioNTech settled with the NIH.
Science Daily: Pharmacology News
JANUARY 1, 2025
Scientists have identified the molecular changes that occur in the brains of aging mice and located a hot spot where much of that damage is centralized. The cells in the area are also connected with metabolism, suggesting a connection between diet and brain health.
Perficient: Drug Development
DECEMBER 30, 2024
This blog provides a detailed explanation of the technical approach for implementing Continuous Deployment (CD) processes within Azure DevOps. It focuses on automating the deployment of solutions to SharePoint environments. This approach not only speeds up the release cycle but also enhances reliability, minimizes errors, and ensures that updates are deployed quickly and effectively.
Drugs.com
DECEMBER 31, 2024
TUESDAY, Dec. 31, 2024 -- A womans binge drinking might be related to her hormones.The female hormone estrogen appears to promote binge drinking in women, a new mouse study published recently in the journal Nature Communications s.
Drug Patent Watch
DECEMBER 29, 2024
FENTORA (fentanyl citrate) Cephalon Patent: 8,119,158 Expiration: Dec 30, 2024 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.
PPD
JANUARY 2, 2025
The biotech industry is a dynamic sector, rapidly evolving and poised for continued growth. Its ability to maneuver persistent drug development challenges, like patient recruitment, trial complexity and rising costs, will ultimately determine its success. Because biotech companies need to remain flexible and agile while remaining on time and on budget they are harnessing innovations to navigate unexpected drug development challenges and leveraging strategies to fill gaps in resources and exper
Science Daily: Pharmacology News
JANUARY 2, 2025
A research team has developed a method for extracting gold from electronics waste, then using the recovered precious metal as a catalyst for converting carbon dioxide (CO2), a greenhouse gas, to organic materials.
Perficient: Drug Development
DECEMBER 30, 2024
Generative AI is rapidly transforming the world around us. From creating stunning artwork to composing music and even writing code, its capabilities are vast and expanding at an unprecedented rate. This blog post will serve as a comprehensive introduction to Generative AI, guiding you through its foundational concepts and exploring the groundbreaking features of ChatGPT.
Drugs.com
DECEMBER 30, 2024
MONDAY, Dec. 30, 2024 -- The United States is lagging behind dozens of nations in its preparation for dealing with its aging population.The U.S. ranks 24 among 143 countries when it comes to ensuring seniors well-being, productivity and security, a.
Alta Sciences
DECEMBER 31, 2024
Inside The Altascientist: Understanding Drug Interaction Factors for Safer, More Effective Therapies pmjackson Tue, 12/31/2024 - 16:23 Intrinsic factors such as age, biological sex, comorbidities, or genetics can potentially alter drug exposure, as can extrinsic factors such as concomitant drugs, supplements, the environment, and food and beverages.
FDA Law Blog: Biosimilars
JANUARY 1, 2025
By Sara W. Koblitz Since the induced infringement finding in GSK v. Teva , the generic industry has feared the death of the skinny label (admittedly stoked by alarmist headlines like my own, see Ding Dong is the Skinny Label (Effectively) Dead? ). This is because, at a minimum, if a skinny-labeled generic is the basis for induced infringement liability, generic manufacturers will certainly think twice about using the skinny label process and still calling themselves AB-rated, which ultimately w
Science Daily: Pharmacology News
JANUARY 1, 2025
Researchers have found the pupil is key to understanding how, and when, the brain forms strong, long-lasting memories.
Perficient: Drug Development
DECEMBER 31, 2024
Artificial Intelligence (AI) is revolutionizing B2B e-commerce, enabling capabilities such as personalized product recommendations, dynamic pricing, and predictive analytics. However, the effectiveness of these AI-driven solutions depends heavily on the quality of the underlying data. Despite AI’s potential, poor data governance remains a significant challenge in the industry.
Drugs.com
DECEMBER 28, 2024
SATURDAY, Dec. 27, 2024 -- Schoolkids will be better able to save the life of a cardiac arrest victim, thanks to a new law signed this week by President Joe Biden.The Cardiomyopathy Health Education, Awareness, Research and Training in Schools.
Codon
JANUARY 2, 2025
Our second book is now available for pre-order. Asimov Press’ latest anthology features nine essays and three works of science fiction. Embracing the book’s technology theme, we did something very special: With the help of three companies — CATALOG, Imagene, and Plasmidsaurus — we’ve encoded a complete copy of the book into DNA, thus merging bits with atoms.
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