Broad Institute
JANUARY 14, 2025
Gene editing extends lifespan in mouse model of prion disease By Allessandra DiCorato January 14, 2025 Breadcrumb Home Gene editing extends lifespan in mouse model of prion disease A single-letter edit in DNA reduces levels of the disease-causing prion protein in the brain and could lead to a preventative, one-time treatment for the deadly neurodegenerative disorder.
BioPharma Drive: Drug Pricing
JANUARY 13, 2025
The company lost more than $3 billion in market value after cutting its forecast for 2025 revenue from its COVID-19 and RSV vaccines.
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BioPharma Drive: Drug Pricing
JANUARY 8, 2025
The regulator is requiring labeling that warns of Guillan-Barré syndrome, although it said data don’t prove a causal link and affirmed the shots’ benefit outweighs their risks.
Science Daily: Pharmacology News
JANUARY 13, 2025
A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
JANUARY 9, 2025
THURSDAY, Jan. 9, 2025 -- Over-the-counter (OTC) drugs acetaminophen and ibuprofen are better at managing dental pain than opioids.People who had their wisdom teeth removed got better results from an acetaminophen/ibuprofen combo than with a.
Nvidia Developer: Drug Discovery
JANUARY 13, 2025
Traditional computational drug discovery relies almost exclusively on highly task-specific computational models for hit identification and lead optimization. Traditional computational drug discovery relies almost exclusively on highly task-specific computational models for hit identification and lead optimization. Adapting these specialized models to new tasks requires substantial time, computational power, and expertisechallenges that grow when researchers simultaneously work across multiple ta
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
JANUARY 8, 2025
Evolutionary biologists are investigating the extent to which ants learn from past experiences. After being attacked by ants from a particular nest, ants behave more aggressively towards others from that same nest.
Drugs.com
JANUARY 13, 2025
MONDAY, Jan. 13, 2025 (HealthDay news) -- The sleep aid Ambien could be allowing toxic proteins to pollute the brain, potentially increasing a persons risk of disorders like Alzheimers disease.Drugs like the main ingredient in Ambien, zolpidem, sup.
Collaborative Drug
JANUARY 9, 2025
Drug Discovery Industry Roundup with Barry Bunin January 9th, 2025
Drug Target Review
JANUARY 14, 2025
Drug discovery scientists spend their days developing and testing complex hypotheses, leveraging data and expertise through workflows that utilise available tools. Operating a workflow, such as the one described in Figure 1, involves several key considerations that affect both the accuracy of results and the efficiency of the research process. Defining the research question A well-defined research question is the cornerstone of an effective scientific workflow in drug discovery.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
JANUARY 10, 2025
The director of the FDA's main drug review office will exit on Jan. 18, according to an email sent to staff. Her departure is one of several announced by high-ranking FDA leaders ahead of the coming administration change.
Science Daily: Pharmacology News
JANUARY 10, 2025
A new study has found that the composition of your gut microbiome helps predict how likely you are to succumb to potentially life-threatening infection with Klebsiella pneumoniae, E.coli and other bugs -- and it may be altered by changing your diet.
Drugs.com
JANUARY 8, 2025
WEDNESDAY, Jan. 8, 2024 -- The antiviral pill Paxlovid might help some patients who are suffering from long COVID.A five-day course of Paxlovid is known to help limit symptoms and shorten illness in patients during an initial bout of COVID-19.
Nvidia Developer: Drug Discovery
JANUARY 13, 2025
Designing a therapeutic protein that specifically binds its target in drug discovery is a staggering challenge. Traditional workflows are often a painstaking. Designing a therapeutic protein that specifically binds its target in drug discovery is a staggering challenge. Traditional workflows are often a painstaking trial-and-error processiterating through thousands of candidates, each synthesis and validation round taking months if not years.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Covalent Modifiers
JANUARY 9, 2025
Tomonori Tamura, Masaharu Kawano, and Itaru Hamachi Chemical Reviews 2024 DOI: 10.1021/acs.chemrev.4c00745 The term undruggable refers to proteins or other biological targets that have been historically challenging to target with conventional drugs or therapeutic strategies because of their structural, functional, or dynamic properties. Drugging such undruggable targets is essential to develop new therapies for diseases where current treatment options are limited or nonexistent.
BioPharma Drive: Drug Pricing
JANUARY 8, 2025
Alongside plans to spin out a new company, the Belgian drugmaker said it will cut some 300 positions, or about 40% of its current workforce.
Science Daily: Pharmacology News
JANUARY 13, 2025
Radiation-induced mutation is unlikely to have induced genetic differences between dog populations in Chornobyl City and the nearby Chornobyl Nuclear Power Plant.
Drugs.com
JANUARY 8, 2025
WEDNESDAY, Jan. 8, 2025 -- Three GLP-1 drugs are best at helping obese and overweight people drop weight, including one that hasnt yet been approved for that purpose.A new evidence review published in the Annals of Internal Medicine shows that the.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Crown Bioscience
JANUARY 8, 2025
How To Choose and Use Drug Resistance Models Drug resistance remains one of the most pressing challenges in cancer drug development, as 90% of cancer deaths worldwide can be attributed to resistance and the drug ineffectiveness associated with it. This ongoing issue can take one of two forms: intrinsic resistance, where cancer cells show inherent insensitivity to therapies from the outset, and required resistance, which develops during treatment as cancer cells adapt and evolve to survive exposu
Covalent Modifiers
JANUARY 9, 2025
Matthew Bogyo, Tulsi Upadhyay, Emily Woods, Stephen Ahator. Kjersti Julin, Franco Faucher, Marijn Hollander, Nichole Pedowitz, Daniel Abegg, Isabella Hammond, Ifeanyichukwu Eke, Sijie Wang, Shiyu Chen, John Bennett, Jeyun Jo, Christian Lentz, Alex Adibekian, Matthias Fellner Research Square Preprint 2025 [link] 10.21203/rs.3.rs-5494070/v1 Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide.
BioPharma Drive: Drug Pricing
JANUARY 9, 2025
The results suggest Bayer’s elinzanetant may help a broader group of women with vasomotor symptoms, which are associated with menopause as well as a common breast cancer therapy.
Science Daily: Pharmacology News
JANUARY 9, 2025
Hydroclimate whiplash -- rapid swings between intensely wet and dangerously dry weather -- has already increased globally due to climate change, with further large increases expected as warming continues, according to a team of researchers.
Drugs.com
JANUARY 10, 2025
FRIDAY, Jan. 10, 2025 -- Ozempic? Wegovy? Zepbound?How about elderberry juice?Elderberry juice might help people lose weight and improve their blood sugar control, a new small-scale study says.People who drank 12 ounces of elderberry juice daily.
PPD
JANUARY 15, 2025
As clinical trials become increasingly complex, particularly in decentralized trials and rare disease studies, sponsors experience increased challenges in site selection, forecasting and resourcing, and patient recruitment and enrollment. Advanced artificial intelligence (AI) and machine learning solutions are revolutionizing critical challenge areas.
Drug Patent Watch
JANUARY 15, 2025
Identifying drug patents is crucial for various stakeholders, including researchers, legal professionals, and business strategists. While Google Patents is a widely used tool for searching patent information, it may not be the most effective solution for identifying drug patents. This article explores the limitations of Google Patents in this context and suggests alternative approaches.
BioPharma Drive: Drug Pricing
JANUARY 13, 2025
Intra-Cellular has had success selling Caplyta, a brain-rebalancing drug that's approved to treat schizophrenia and bipolar depression.
Science Daily: Pharmacology News
JANUARY 9, 2025
A battery that needs feeding instead of charging? This is exactly what researchers have achieved with their 3D-printed, biodegradable fungal battery. The living battery could supply power to sensors for agriculture or research in remote regions. Once the work is done, it digests itself from the inside.
Drugs.com
JANUARY 13, 2025
Monday, Jan. 13, 2025 -- A fecal transplant could help people whose type 1 diabetes has fouled up their digestive system.Swallowing a handful of capsules filled with donor feces helped ease gut pain, nausea, bloating and diarrhea stemming from.
Perficient: Drug Development
JANUARY 15, 2025
Its truly an exciting and proud moment for our QA India Practice, as we have achieved an incredible milestone: a 50/50 gender ratio by the end of 2024. While we continue to stand out with many QA achievements, we mark gender parity as our long-term goal. This progress in gender ratio sets a benchmark for the entire workforce by integrating committed, talented women into all areas, from entry-level to leadership roles.
Drug Patent Watch
JANUARY 14, 2025
UZEDY (risperidone) Teva Patent: 10,736,965 Expiration: Jan 12, 2025 See More … For more information on how DrugPatentWatch can help with your pharmaceutical business intelligence needs, contact admin@DrugPatentWatch.com or visit www.DrugPatentWatch.
BioPharma Drive: Drug Pricing
JANUARY 12, 2025
The biotech plans to use the funding to advance clinical testing of an epigenetic silencing therapy it hopes could treat chronic hepatitis B infections.
Science Daily: Pharmacology News
JANUARY 9, 2025
Sabre-toothed predators -- best know from the infamous Smilodon -- evolved multiple times across different mammal groups. A new study reveals why: these teeth were 'functionally optimal' and highly effective at puncturing prey.
Drugs.com
JANUARY 10, 2025
FRIDAY, Jan. 10, 2025 -- The clock is running for people whove been diagnosed with dementia, but the time they have left depends on their age.Average life expectancy for people with dementia is largely based on their age at diagnosis, researchers f.
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