HHS to cut 10,000 staff in major restructuring under RFK Jr.
BioPharma Drive: Drug Pricing
MARCH 27, 2025
The FDA will lose about 3,500 employees under the plans, although HHS said drug, medical device and food reviewers will not be affected.
Trending Articles
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Cold plunges actually change your cells
Science Daily: Pharmacology News
MARCH 28, 2025
Cold water immersion for seven days significantly improves cellular resilience and autophagic function, helping cells manage stress better. This adaptation could enhance health and longevity, potentially preventing diseases and slowing aging at a cellular level.
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Exercise of any kind boosts brainpower at any age
Science Daily: Pharmacology News
MARCH 25, 2025
Whether it's an early morning jog, or a touch of Tai Chi, groundbreaking research shows that any form of exercise can significantly boost brain function and memory across children, adults, and older adults.
Measles Outbreak Leads to Dangerous Vitamin A Toxicity
Drugs.com
MARCH 28, 2025
FRIDAY, March 28, 2025 -- As a measles outbreak spreads across U.S., doctors are now seeing a new and unexpected danger: Children getting sick from taking too much vitamin A.At Covenant Childrens Hospital in Lubbock, Texas, several unvaccinated c.
Bridging Innovation & Patient Care: The Growing Role of AI
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
1,2,3‐Triazole Tethered Spiro[Indoline‐Oxirane] Derivatives Induce Anticancer Effects in Human Hepatoma Cells
Chemical Biology and Drug Design
MARCH 26, 2025
Synthesis and anticancer studies of spiro[indoline-oxirane] derivatives. ABSTRACT Epoxides are well-known compounds as anticancer agents. In this article, we present the synthesis of novel 3-phenyl-1-((1-aryl-1 H -1,2,3-triazol-5-yl)methyl)spiro[indoline-3,2-oxiran]-2-one derivatives by the regioselective reaction of sulfur ylides with 1,2,3-triazole-tethered isatins and their anticancer effects on hepatocellular carcinoma (HCC) cells HepG2 and HCCLM3.
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First Prader-Willi drug to reduce hunger approved by FDA
BioPharma Drive: Drug Pricing
MARCH 26, 2025
Clearance of Vykat unlocks what analysts anticipate will be a lucrative market opportunity for Soleno Therapeutics.
More Type 1 Diabetics Are Obese, Taking GLP-1 Drugs
Drugs.com
MARCH 31, 2025
MONDAY, March 31, 2025 -- Use of cutting-edge weight-loss drugs like Ozempic and Zepbound has increased dramatically among people with type 1 diabetes, raising safety concerns among experts, a new study says.Both adults and children with type 1.
Collaborative Drug Discovery's Inaugural Canadian User Group Meeting
Collaborative Drug
MARCH 27, 2025
Collaborative Drug Discovery's Inaugural Canadian User Group Meeting
7 Steps to Define a Data Governance Structure for a Mid-Sized Bank (Without Losing Your Mind)
Perficient: Drug Development
MARCH 25, 2025
A mid-sized bank I was consulting with for their data warehouse modernization project finally realized that data isn’t just some necessary but boring stuff the IT department hoards in their digital cave. It’s the new gold, the ticking time bomb of risk, and the bane of every regulatory report that’s ever come back with more red flags than a beach during a shark sighting.
From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Peter Marks, FDA’s top vaccine official, resigns
BioPharma Drive: Drug Pricing
MARCH 29, 2025
In his resignation letter, Marks cited disagreement with HHS Secretary Robert F. Kennedy Jr., who he said pushed “misinformation and lies.
'Low-sugar' vaccine can provide broad immunity against coronavirus variants
Science Daily: Pharmacology News
MARCH 25, 2025
Early animal studies show that a single vaccine could protect the recipient from different variants of the coronaviruses that cause COVID-19, the flu and the common cold. In addition to creating antibodies that target a specific region of the spike protein that doesn't mutate, the vaccine removes the sugar coat from the virus that allows it to hide in the body.
Top FDA Vaccine Official Quits, Warns of Vaccine Misinformation
Drugs.com
MARCH 31, 2025
MONDAY, March 31, 2025 -- A top vaccine official at the U.S. Food and Drug Administration (FDA) is stepping down, warning that vaccine misinformation is coloring the countrys top health decisions.Dr. Peter Marks, director of the FDAs Center for Bi.
Therapeutic Oligos 2025 Keynote Speakers Announced
Elrig
MARCH 25, 2025
Therapeutic Oligos 2025 Keynote Speakers Announced ELRIG Announces Prof Rory Johnson and Dr Shalini Andersson as Keynote Speakers at Therapeutic Oligonucleotides 2025 Cambridge, UK, 25 March 2025: ELRIG, a not-for-profit, volunteer-led organisation for the drug discovery community, today announced the keynote speakers for Therapeutic Oligonucleotides 2025 taking place at the AstraZeneca R&D site in Gothenburg, Sweden from 1415 May.
How Machine Learning Drives Clinical Trial Efficiency
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Mastering AWS Infrastructure as Code with Pulumi and Python
Perficient: Drug Development
MARCH 27, 2025
Pulumi is a modern Infrastructure as Code (IaC) tool that allows you to define, deploy, and manage cloud infrastructure using general-purpose programming languages. Unlike Terraform, which uses HCL, Pulumi enables you to define infrastructure using Python, making it easier for developers to integrate infrastructure with application code. What Youll Learn How Pulumi works with AWS Setting up Pulumi with Python Deploying various AWS services with real-world examples Best practices and advanced tip
Cell, gene therapy makers lose a champion at FDA with exit of Peter Marks
BioPharma Drive: Drug Pricing
MARCH 31, 2025
Marks’ resignation leaves the field without a regulator many view as “integral” to its progress over the last decade.
New Evidence Links Microplastics with Chronic Disease
Science Daily: Pharmacology News
MARCH 25, 2025
Tiny fragments of plastic have become ubiquitous in our environment and our bodies. Higher exposure to these microplastics, which can be inadvertently consumed or inhaled, is associated with a heightened prevalence of chronic noncommunicable diseases, according to new research.
Organ Transplant Patient Dies After Contracting Rabies
Drugs.com
MARCH 28, 2025
FRIDAY, March 28, 2025 -- A Michigan resident has died after receiving an organ transplant infected with rabies, state health officials said Wednesday.The patient got the transplant at an Ohio hospital in December and passed away the following.
Deliver Fast, Flexible Clinical Trial Insights with Spotfire
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
The Benefits of Digital Transformation in Generic Drug Development
Drug Patent Watch
MARCH 27, 2025
Revolutionizing Generic Drug Development: The Power of Digital Transformation As the pharmaceutical industry continues to evolve, one thing is clear: digital transformation is no longer a luxury, but a necessity. At the forefront of this revolution is the generic drug development sector, where innovative technologies are streamlining processes, reducing costs, and improving patient outcomes.
From FinOps Bean Counting to Value Harvesting: The Rise of Unit Economics
Perficient: Drug Development
MARCH 25, 2025
Applying FinOps concepts to your cloud consumption is not new. Its often treated as an IT hygiene task: necessary but not strategic. And while cost optimization and waste reduction are worthy efforts, its all too common to see these activities fall victim to higher daily priorities. When they are in focus, its often attempted by looking for low-hanging wins using cloud-native services that arent overly interested in delivering a comprehensive picture of cloud spend.
Lilly hits same Alzheimer’s roadblock in Europe as Eisai, Biogen
BioPharma Drive: Drug Pricing
MARCH 28, 2025
Key regulators are not recommending Lilly’s Kisunla be cleared for the European market. The company says it plans to appeal the verdict, a strategy successfully employed by Eisai.
A hit of dopamine tells baby birds when their song practice is paying off
Science Daily: Pharmacology News
MARCH 25, 2025
By watching the ebb and flow of the brain's chemical signals, researchers are beginning to disentangle the molecular mechanisms underlying the intrinsic motivation to learn. In a new study of zebra finches, researchers show that a hit a dopamine tells baby birds when their song practice is paying off. The findings suggest that dopamine acts like an internal 'compass' to steer their learning when external incentives are absent.
Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Novo Nordisk To Pay $2 Billion for New Weight Loss Drug
Drugs.com
MARCH 25, 2025
TUESDAY, March 25, 2025 -- Novo Nordisk, a Danish pharmaceutical company, has signed a major deal worth up to $2 billion for the rights to a new obesity and diabetes drug, the company announced March 24. The drug, called UBT251, is being developed.
How Japan and South Korea are Shaping the Next Era of Clinical Development
Fierce BioTech
MARCH 25, 2025
How Japan and South Korea are Shaping the Next Era of Clinical Development Discover why Japan and South Korea are emerging as clinical trial powerhouses, offering cutting-edge infrastructure, streamlined regulations, and unique commercial advantages. Download now to explore key opportunities and compare study start-up and approval timelines with the U.S. smarcus Tue, 03/25/2025 - 09:54 Discover why Japan and South Korea are emerging as clinical trial powerhouses, offering cutting-edge infrastruc
Support Systems: Building Your Multiple Sclerosis (MS) Care Team
Antidote
MARCH 26, 2025
Living with multiple sclerosis (MS) can sometimes feel like youre navigating an unpredictable roadone with unexpected twists, turns, and detours. Theres so much information to absorb, decisions to make, and changes to navigate. At times, it might feel isolatingbut heres the truth: You are not alone in this.
Wave to seek approval of Duchenne drug after mid-stage study data
BioPharma Drive: Drug Pricing
MARCH 26, 2025
The company plans to file next year for an accelerated clearance of its "exon-skipping" treatment, which would compete with one of Sarepta's medicines.
A safe nuclear battery that could last a lifetime
Science Daily: Pharmacology News
MARCH 26, 2025
Lithium-ion batteries, used in consumer devices and electric vehicles, typically last hours or days between charges. However, with repeated use, they degrade and need to be charged more frequently. Now, researchers are considering radiocarbon as a source for safe, small and affordable nuclear batteries that could last decades or longer without charging.
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