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Transforming high-throughput screening with mass spectrometry

Drug Discovery World

HTS as a tool for drug discovery has evolved rapidly since the origin of the technique in the 1990s. Trapped ion mobility spectrometry: Improving the specificity of MALDI-MS-based HTS . Wagner, MALDI imaging mass spectrometry: Bridging biology and chemistry in drug development, Bioanalysis, 2011, 3: 2427–2441, [link].