Transforming high-throughput screening with mass spectrometry
Drug Discovery World
OCTOBER 14, 2022
HTS as a tool for drug discovery has evolved rapidly since the origin of the technique in the 1990s. Figure 3: Quantitative analysis of a drug-like molecule (MW 543 Da), showing the elimination of interfering assay background and the consequent improvement in quantitation using TIMS in conjunction with MALDI-MS/MS. Ritorto, R.
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