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Transforming high-throughput screening with mass spectrometry

Drug Discovery World

HTS is widely used by pharmaceutical companies to identify compounds (or ‘hits’) that show pharmacological activity, which are used as starting points to optimise medicines during the drug discovery process. Trapped ion mobility spectrometry: Improving the specificity of MALDI-MS-based HTS . Weigt, C.A. Parrish, J.A.