article thumbnail

Drug repurposing: The benefits, risks and what we learned from Covid-19

Drug Discovery World

What are benefits of drug repurposing and why do clinical drug trials so often fail? Diana Spencer summarises the key messages from the ‘Drug Repurposing: Challenges and Opportunities’ Symposium held at the 19th World Congress of Basic & Clinical Pharmacology (WCP) 2023.

article thumbnail

Advanced 3D cell-based technologies

Drug Target Review

puts an end to the previous mandate that all drugs need to be tested on animals prior to human clinical trials. Prior to this European Union Parliament, in 2021, voted for animal testing phase out. The US FDA Modernisation Act 2.0.,

article thumbnail

Everything Wrong with Mouse Studies (Kinda)

Codon

They had “seen no evidence of [graft-versus-host disease] in any patient,” wrote surgeon Steven A. Each animal had a different microbiome. The FDA used to require animal tests before a human drug trial could proceed; they reversed that decision in January. A third experiment found no effect.

DNA 52