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A therapy candidate for fatal prion diseases turns off disease-causing gene

Broad Institute

Science (2024) Related content New gene delivery vehicle shows promise for human brain gene therapy My Quest to Cure Prion Disease — Before It’s Too Late | Sonia Vallabh | TED Prion diseases lead to rapid neurodegeneration and death and are caused by misshapen versions of the prion protein in the brain.

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Gylden’s gold platform trains T cells to kill viruses

Drug Target Review

One such breakthrough comes from Gylden Pharma , a clinical-stage biotech developing T cell-priming vaccines to combat global infectious disease threats. Rademacher explained that their approach bypasses the need for traditional animal testing: Everybody asks us why we don’t test our vaccines in monkeys and rabbits.

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Levers for Biological Progress

Codon

Amodei also imagines the ways AI could accelerate biological research and yield miraculous cures in the 21st century; everything from the prevention and treatment of nearly all infectious and inherited diseases to the elimination of most cancers. This essay focuses on how we might do both, specifically for the cell. Subscribe to Asimov Press.

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