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The current landscape of protein drug development is characterised by accelerated timelines where new drugs are approved in months rather than years. For example, advances in media and feeds have contributed to higher cell proteinexpression by optimising nutrient availability and reducing accumulation of waste products within a culture.
By Greta Friar, Whitehead Institute June 27, 2024 Images of a mouse brain show the effect of a technology called CHARM in turning off the expression of a gene in the brain. Like Cas9, ZFPs can serve as guide proteins to direct the tool to a target site in DNA. Credit: Neumann EN, Bertozzi TM, et al.
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