Remove Animal Testing Remove Laboratories Remove Protein Expression
article thumbnail

A therapy candidate for fatal prion diseases turns off disease-causing gene

Broad Institute

By Greta Friar, Whitehead Institute June 27, 2024 Images of a mouse brain show the effect of a technology called CHARM in turning off the expression of a gene in the brain. However, with a strong therapy design and promising laboratory results in hand, the researchers have good reason to be hopeful.

Disease 142
article thumbnail

Rapid delivery of toxicological material

Drug Target Review

Rapid delivery of IND-enabling Tox testing is crucial for a timely IND submission Advanced technologies enabling increasingly rapid timelines from vector construction to good manufacturing practice (GMP) manufacture brings the prospect of ever shorter timelines to IND readiness. FDA no longer has to require animal testing for new drugs.