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Animaltesting has had an influential role in almost every medical breakthrough in the last 100 years. Further, animals are essential in assessing drugs and vaccine safety. Approximately 26 million animals are used in the USA every year for research purposes.
The guidance looks very different from the draft that was published in February 2020, including changes in the scope of the guidance, its sponsorship, and the removal of all mentions of nonhuman primates for animaltesting. Nonclinical studies encompass much more than just animal studies.
It may seem that if researchers are sufficiently concerned about the welfare of lab animals, the best thing to do would be to stop using animals altogether. However, a multitude of factors—from institutional inertia to a global animal-testing industry worth billions of dollars —make this outcome unlikely.
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Without mouse models, we may never have developed polio and meningitis vaccines, organ transplants, GLP-1 drugs, gene therapies , or any other number of transformative treatments. Today, somewhere on the order of 30 million rodents are used yearly in biomedical research in the U.S.
In the fast-moving world of drug discovery and vaccine development, the most transformative breakthroughs often emerge where cutting-edge science meets bold innovation. One such breakthrough comes from Gylden Pharma , a clinical-stage biotech developing T cell-priming vaccines to combat global infectious disease threats.
Though my focus in this essay is narrow — I don’t discuss bottlenecks in clinical trials, human disease, or animaltesting — I hope others will take on these challenges in similar essays. This essay focuses on how we might do both, specifically for the cell. Subscribe to Asimov Press.
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