SARS-CoV-2 main protease. Crowdsourcing, peptidomimetics and fragments
Molecular Design
JULY 18, 2020
The binding mode observed for 1 is shown below in Figure 1 and it’s likely that the groove region will need to be more fully exploited (this article will give you an idea of the sort of thing I have in mind) in order to achieve acceptable potency if the aldehyde warhead is replaced by nitrile. by forming a ring).
52 
Let's personalize your content