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Betulinic acid reduces inflammation in rats with sepsis?induced myocardial dysfunction by inhibiting TLR4/MyD88/NF??B signaling pathway

Chemical Biology and Drug Design

Then, cardiac function parameters were assessed using echocardiography, myocardial injury markers were quantified via biochemical assays, and myocardial histopathological injuries were observed through H&E staining. The protein expression levels of TLR4, Myd88, and NF-κB in myocardial tissue were assessed through western blot analysis.