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Not all neoantigens are created equal

Drug Target Review

During the process of transformation from a normal cell into a cancer cell, a cell acquires a series of changes, or mutations, in its DNA. But DNA mutations can also result in changes to the proteins that are displayed on the surface of the cancer cell. These mutations are called clonal mutations or clonal neoantigens.

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Can Global Genomic Surveillance Forecast the Next Pandemic?

PLOS: DNA Science

Many of the links below are to some of the 100+ DNA Science posts that I wrote during the pandemic. Other genomic databases were retooled for the huge datasets that COVID was generating, such as the Cloud Institute for Microbial Bioinformatics, begun in 2014 and rechristened the COVID-19 Genomics UK Consortium ( COG-UK ).

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Kickstarting the use of AI for biotechs: part two

Drug Target Review

More explanation and practical tips for using these technologies will be explored in future articles. 2 AlphaFold 3 has been built to model DNA, RNA and smaller molecules (ligands). 5 Several major technology areas are not included above, such as cheminformatics and bioinformatics. Alphafold 3.0:

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Reaching cruising altitude: New discovery tools to target RNA

Dark Matter Blog

Today, we are pleased to announce that our article describing one such platform: “ PEARL-seq, A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions ” was published in ACS Chemical Biology. With millions of DNA sequences, we could precisely measure the rate of RT pausing at each position of the RNA.

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Leading Microbiome Researcher Dr. Eric Pamer Joins Diversigen’s Scientific Advisory Board

The Pharma Data

He has published more than 200 articles and book chapters. Diversigen provides consultative end-to-end solutions for sequencing, bioinformatics, and statistical analysis for the study of the microbiome of living organisms and environments. About Diversigen Inc. Diversigen, Inc. is a subsidiary of OraSure Technologies Inc.

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Next Generation Sequencing (NGS) in Clinical Trials: Challenges and Opportunities

Vial

Transforming Genomics Research Next-generation sequencing (NGS) enables comprehensive genome sequencing and has transformed genomics research, offering vastly improved capabilities for analyzing DNA and RNA in a high-throughput and cost-effective manner. Satam et al.

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Is That DNA Dangerous?

Codon

Tessa Alexanian and Max Langenkamp build computational DNA screening tools for a living. This article concludes our mini-issue. But today, rapid advances in DNA synthesis have made it possible for would-be bioterrorists to make pathogens, rather than buy them. The two of us work on computational DNA screening tools for a living.

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