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Read the Article Rare Roundup The Jackson Laboratory offers “Exploring Rare Disease Through Translational Research” MiniCourse Human health is incredibly complex; developing safe, effective treatments requires knowledge of molecular mechanisms, cellbiology, and drug administration.
In recent years, a novel approach known as condensate biology has emerged, revolutionising the way researchers think about drug discovery and development. The aim is to establish condensate biology as a fundamental branch of cellbiology – “cellbiology 2.0”
After the corresponding transfection or treatment with inhibitor of catenin-responsive transcription-3 (iCRT-3), abovementioned CRC cell biological behaviors as well as expression levels of HOXB7 and β-catenin were evaluated. μM THA dwindled CRC cell viability, migration, and invasion, and facilitated apoptosis.
With its disruptive pipetting technology, SEED Biosciences is bridging the gap between the capabilities in liquid handling and the opportunities in single cellbiology. He is the recipient of multiple awards for young entrepreneurs, including the Venture Leaders Prize given to top Swiss entrepreneurs.
DDP-resistant NPC cells were established by treatment with DDP at increased concentrations (2, 4, 6, 8, or 10 μg/mL). Cell biological behaviors were assessed via cell function experiments. MicroRNA-577 and EIF5A2 mRNA expressions were detected by qRT-PCR.
Similar sentiments have been expressed elsewhere, such as by Brandon Stell, the founder of PubPeer , a website where anyone can leave comments about academic articles. Still, shortly after I read Mastroianni’s article, Ben Recht asked on Twitter if there were any articles presenting “a positive case for peer review.”
With its disruptive pipetting technology, SEED Biosciences is bridging the gap between the capabilities in liquid handling and the opportunities in single cellbiology. He is the recipient of multiple awards for young entrepreneurs, including the Venture Leaders Prize given to top Swiss entrepreneurs.
Their findings are published online in Nature CellBiology. “We are amazed by the efficiency of small-molecule PROTAC in simultaneously targeting EZH2 and cMyc in cancer cells.”
Turning this tide, Professor Jens Christian Schwamborn, a cellbiology expert at the University of Luxembourg and co-founder of OrganoTherapeutics , is leading a groundbreaking effort to transform our understanding and treatment of these debilitating diseases.
Shortly after finishing my studies, I landed my first job in industry working on cellbiology research for several disease indications. I would keep track of developments in the industry through research articles, conferences and my network.
That creates a resource for scientists, including data science researchers who want to apply machine learning to cell images; now they have more than 200,000 cells they can play with. It also allows scientists to explore hypotheses about the cellbiology of undifferentiated stem cells.
This article first appeared on MDLinx.
Particularly in TNBC, collagen remodeling is seen in the stromal compartment [ 3 ]. Assessing Collagen Features at a Finer Level of Detail.
Copper depletion may reduce breast cancer relapse in patients at high risk
Website, Weill Cornell Medicine, Sandra and Edward Meyer Cancer Center.
In this article, we focus on the contribution of genomics to the development of modern precision medicine through the use and interpretation of genome-wide association studies (GWAS). Network expansion of genetic associations defines a pleiotropy map of human cellbiology. 53 , 1527–1533 (2021).
This is the first article in our new column. Credit: Oriane Hidalgo Per the book CellBiology by the Numbers , each base pair of DNA occupies 1 nm 3 of space. These are pieces that are too short to run in our quarterly Issues.
This is Codon Digest, a weekly roundup of research papers, news articles, and industry highlights about engineered biology. ” — Samuel Butler , 1878 (* = My picks) AI + Bio Characterizing the interaction conformation between T-cell receptors and epitopes with deep learning. Thanks for skimming. Might be useful!
Nature CellBiology. No company makes them for commercial sale in those countries, and hospitals and pharmacies don’t stock them,” writes Maryn McKenna in a recent WIRED article. Trends in Biotechnology. Read Julia for biologists. Nature Methods. Science Advances. .
Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature CellBiology. A new paper engineers a communication network between cells using DNA instead. Read A nice article from Aatish Bhatia about how A.I.
Read Stem cells were induced to form insulin-secreting pancreas cells and then transplanted into diabetic mice, where they successfully restored glucose levels. Nature CellBiology. A new paper engineers a communication network between cells using DNA instead. Read A nice article from Aatish Bhatia about how A.I.
Few journal articles were written about the project using her (or anyone’s) name before 2010. When Louis Miller, now Chief of Malaria CellBiology at the NIH, attended a malaria conference in Shanghai in 2008, he asked: Who discovered artemisinin? Miller and Su published an article on Tu’s story in Cell in 2011.
They achieved this by treating mouse fetal ovaries with an enzyme mixture to break them apart into single cells, isolating the ovarian supporting cells, and mixing them with human PGC-like cells to form aggregates, which were then cultured in liquid media for up to 120 days.
Dr. Hartmann has published over 40 research articles, reviews and book chapters. Here we propose to uncover the cell-type specific transcriptional pathways governed by cortisol levels in the frontal cortex, which comprises brain areas that are determinants of high-level cognition and mood, and therefore relevant to the symptomology of PTSD.
I then took over management of a research group, initially running cellbiology research and then preclinical development.” Dan then took over management of a cell research group, initially running a cellbiology research project then preclinical development.
She has a PhD in Microbiology and CellBiology from the University of Illinois, followed by work in biochemistry as a post-doctoral fellow at UCSF. About the authors Ann E Cleves Ann is VP of Application Science for Optibrium s BioPharmics Division, which focuses on 3D computational modelling for molecular design.
Read There’s a news article that breaks down this work. Nature CellBiology. Read *Open-endedness in synthetic biology: a route to continual innovation for biological design. Read Just for Fun High protein-containing new food by cell powder meat. Favate J.S. Debès C. Rockweiler N.B. Nature Biotechnology.
She has a background in cellbiology, biophysics and pharmacology and was a professor and Chair at the University of Kansas for over 20 years. About the authors Dr Lisa Stehno-Bittel is President and Founder of Likarda and Professor Emeritus at University of Kansas Medical Center.
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