Codon

JULY 27, 2023

I could write an entire article in response, but if you want to go deeper into this subject, I suggest you read it in full. From an article in Science : “After 6 months, the most promising varieties had their lignin content reduced by 49.1% Transcription factors are proteins that bind to DNA and control gene expression.

Therapies 52

Therapies RNA DNA Engineering 52

Codon

APRIL 30, 2023

Yeast die for two reasons: Either their nucleolus (where the DNA is kept) degrades and dies, or their mitochondria whimpers out and they stop making energy. The vaccine printer can make lots of different types of vaccines, including protein, DNA, and mRNA ones, but I’m sure this is all quite expensive right now. From Zhang et al.

Vaccine 52

Vaccine DNA Engineering RNA 52

Codon

APRIL 30, 2023

Yeast die for two reasons: Either their nucleolus (where the DNA is kept) degrades and dies, or their mitochondria whimpers out and they stop making energy. The vaccine printer can make lots of different types of vaccines, including protein, DNA, and mRNA ones, but I’m sure this is all quite expensive right now. From Zhang et al.

Vaccine 52

Vaccine DNA Engineering RNA 52

Drug Target Review

DECEMBER 28, 2023

During the process of transformation from a normal cell into a cancer cell, a cell acquires a series of changes, or mutations, in its DNA. But DNA mutations can also result in changes to the proteins that are displayed on the surface of the cancer cell. Neoantigens are recognised as non-self and trigger an immune response.

Bioinformatics 105

Bioinformatics Immune Response DNA Vaccine 105

Codon

APRIL 9, 2023

Thousands of transcription factors — proteins that bind DNA and control gene expression — were studied in human cells. Read DNA Sequencing & Synthesis *Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing. Bergs A.C.F. Nature Communications. Porta-de-la-Riva M. Nature Methods.

Therapies 52

Therapies RNA Engineering Vaccine 52

Drug Target Review

DECEMBER 13, 2024

Innovations in payload substances, such as topoisomerase inhibitors (topo-1i), and next-generation DNA- damaging agents to replace older, more toxic agents. Engineering sites on the antibody to enable specific and consistent attachment of the cytotoxic drug to achieve an optimal drug-to-antibody ratio (DAR).

Therapies 98

Therapies Treatment Clinical Trials Drugs 98

PLOS: DNA Science

MAY 16, 2024

Many of the links below are to some of the 100+ DNA Science posts that I wrote during the pandemic. • identifies parts of the virus to target to provoke an immune response from a vaccine. After sequencing, artificial intelligence adds context to RNA and DNA sequences through comparisons to others.

Virus 98

Virus DNA RNA Vaccine 98

Codon

DECEMBER 12, 2024

” The report accompanies an article in Science , also released today, entitled “Confronting Risks of Mirror Life.” For the article in Science , more than 30 scientists from ten countries are calling on the broader community to confront the risks of mirrored life. ” But what, exactly, is a mirrored organism?

RNA 104

RNA DNA Vaccine Virus 104

Codon

APRIL 16, 2023

Skin microbes can trigger strong immune responses. These microbes were engineered to express tumor antigens that could “elicit T cells that were licensed by the commensal immune program but specific for a tumor,” including both CD4+ and CD8+ T cells, according to the study. coli DNA using a Retro-Cascorder.

Engineering 52

Engineering DNA RNA Science 52

Drug Target Review

DECEMBER 11, 2024

Discovering and optimising potent therapeutics that direct the immune response against these targets. This requires a deep understanding of how the key components of the immune system – antibodies and TCRs – recognise and interact with their targets on cancer cells.

Immune Response 52

Immune Response Engineering Therapies Small Molecule 52

PLOS: DNA Science

FEBRUARY 20, 2025

All 38 editions of the life science textbooks I’ve written have chapters on immunology that clearly define vaccine: “an inactive, disabled, or part of a pathogen that stimulates an immune response. My 500th post here at DNA Science , from 2023, was In Celebration of Vaccines – for good reason.

Vaccine 94

Vaccine Science RNA Disease 94

New Drug Approvals

APRIL 4, 2025

Hindawi Oxidative Medicine and Cellular Longevity, Volume 2018, Article 3420187) [0007] Glaucoma is made up of a collection of eye diseases that cause vision loss by damage to the optic nerve and retinal ganglion cells (RGCs). Uveitis is responsible for an estimated 30,000 new cases of legal blindness annually in the USA.

Disease 62

Disease Treatment Clinical Trials Therapies 62

PLOS: DNA Science

JULY 25, 2024

I’ve included links to some of my articles, where relevant. A virus that directly attacks the immune response presents a special challenge. The post Anthony Fauci’s Memoir “On Call” Journeys through a Half Century of Plagues Amid the Politics of Public Health appeared first on DNA Science.

Virus 96

Virus Science Vaccine Government 96