MiR?34 by targeting p53 induces apoptosis and DNA damage in paclitaxel?resistant human oral squamous carcinoma cells
Chemical Biology and Drug Design
APRIL 15, 2023
The chemosensitive effects of miR-34 is mediated through increasing DNA damage and apoptosis in a p53 depended manner. The present study aimed to evaluate the effects of miR-34 restoration in OECM-1 oral cancer resistant to paclitaxel (OECM-1/PTX) and its underlying mechanisms through p53-mediated DNA damage and apoptosis.
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