Chemical Biology and Drug Design

APRIL 15, 2023

The chemosensitive effects of miR-34 is mediated through increasing DNA damage and apoptosis in a p53 depended manner. The present study aimed to evaluate the effects of miR-34 restoration in OECM-1 oral cancer resistant to paclitaxel (OECM-1/PTX) and its underlying mechanisms through p53-mediated DNA damage and apoptosis.

DNA 100

DNA Protein Expression Research 100

Chemical Biology and Drug Design

DECEMBER 12, 2024

Biochemical kits was utilized for checking the ATP, mitochondrial DNA, MDA, GSH, and Fe 2+ levels in the Huh7 cells, and western blot for measuring the ferroptosis and AMPK/mTOR related-protein expression levels.

Protein Expression 100

Protein Expression DNA Regulations Research 100

Drug Target Review

JULY 5, 2023

A good introduction to the use of CHO cells for biotherapeutics production can be found in an article commemorating the 20th anniversary of the approval of a product produced using CHO cells. These sites are typically in areas of open chromatin and associated with highly expressed genes. Biotechnol. 2022), 349: 53-64.

Engineering 105

Engineering DNA Laboratories Production 105

Alta Sciences

APRIL 17, 2024

In this blog article, we review some of these areas of investigation where Altasciences has robust expertise and solution offerings. According to a 2022 article published in Molecular Psychiatry, treatment resistance affects 20 to 60% of patients with psychiatric disorders. Asia, and Europe.

Drug Development 52

Drug Development Treatment FDA Approval Drugs 52

Codon

APRIL 9, 2023

.” This technology could be used to design protein therapeutics that can bind to, and “shut down,” harmful or misfolded proteins in living cells. Thousands of transcription factors — proteins that bind DNA and control gene expression — were studied in human cells. Bergs A.C.F.

Therapies 52

Therapies RNA Engineering Vaccine 52

Codon

FEBRUARY 16, 2025

This article is best experienced on our website. Building a Circuit Much like electronic circuits, which use wires and transistors to create or process signals, a synthetic gene circuit is a network of biological parts — DNA, RNA, and proteins — that process inputs and generate outputs. 3 Subscribe to Asimov Press.

DNA 84

DNA RNA Engineering Small Molecule 84

Drug Target Review

JANUARY 20, 2025

This article explores how innovations in precision medicine are reshaping clinical trials, followed by a discussion on Project Optimus and its impact on dose optimisation. Genetic factors Mutations or alterations in tumour DNA (eg, EGFR mutations in lung cancer or HER2 amplification in breast cancer) are key targets of precision medicine.

Clinical Trials 52

Clinical Trials Trials Drugs Drug Development 52