Drug Patent Watch

DECEMBER 10, 2024

This shift has led to the emergence of integrated contract development and manufacturing organizations (CDMOs), which provide end-to-end support for drug developers. In this article, we will delve into the benefits of working with integrated CDMO services and explore how they can streamline the drug development and manufacturing process.

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Drug Development Compliance Pharmaceutical Companies Drugs 96

Drug Patent Watch

DECEMBER 10, 2024

India has long been recognized as a significant player in the global pharmaceutical industry, particularly in the production of generic drugs. This article delves into India’s growing importance in generic drug API manufacturing, highlighting the key factors contributing to its success and the challenges it faces.

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Government Pharmacy Drugs Pharmaceuticals 97

Drug Patent Watch

FEBRUARY 11, 2025

The Dark Side of Innovation: How Companies Use Drug Patents to Block Competitors As we celebrate the breakthroughs in medical research and the development of life-saving treatments, it's essential to acknowledge the complex landscape of pharmaceutical innovation. One of the most effective tools in their arsenal is the use of drug patents.

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Drugs Treatment Marketing Production 96

Drug Patent Watch

DECEMBER 11, 2024

The pharmaceutical industry, particularly the generic drug sector, faces significant challenges in adopting sustainable practices. This article outlines key considerations and strategies for developing a sustainable generic drug development strategy. “Generics are known for their cost-effectiveness.

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Drug Development Compliance Drugs Pharmaceuticals 98

Drug Target Review

AUGUST 30, 2023

Advancing drug discovery for pain disorders: human iPSC-based approach Drug discovery relies on the use of relevant model systems. Therefore, to advance drug discovery in the field, screens on human cellular models such as such as specialised sensory neurons (nociceptors) are necessary.

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Drugs RNA Treatment Disease 106

Drug Patent Watch

MARCH 3, 2025

Breaking Down Barriers: The Power of Global Research Collaborations in Generic Drug Development As the world grapples with the complexities of healthcare, one thing is clear: the need for innovative solutions has never been more pressing. The benefits of international collaborations in generic drug development are multifaceted.

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International Drug Development Drugs Treatment 88

Drug Patent Watch

FEBRUARY 12, 2025

Accelerating Generic Drug Development: Strategies for Success As a pharmaceutical professional, you know how crucial it is to navigate the complex landscape of generic drug development. The generic drug development process involves several stages, from patent research to regulatory approvals.

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Drug Development Drugs Compliance Regulations 81

Chemical Biology and Drug Design

MARCH 14, 2025

Fragment-based drug discovery (FBDD) was applied to cytochrome P450 3A4 reconstituted in Nanodiscs (NDs) with various lipid compositions. The choice of ND lipid influenced drug membrane interactions and fragment hit rates, demonstrating the critical role of the membrane environment in fragment screening for membrane proteins.

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Fragment Screening Pharmacokinetics Drugs Marketing 100

Drug Target Review

JANUARY 14, 2025

Drug discovery scientists spend their days developing and testing complex hypotheses, leveraging data and expertise through workflows that utilise available tools. Defining the research question A well-defined research question is the cornerstone of an effective scientific workflow in drug discovery. provide more general information.

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Drugs Protein Expression Science Research 69

Drug Target Review

MARCH 24, 2025

Sujeegar Jeevanandam, an expert with 13 years of experience in life sciences R&D, offers valuable insights into the current state and future trajectory of artificial intelligence in drug discovery. This breakthrough could fundamentally change how drugs are developed and tested.

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Clinical Trials Animal Testing Drugs Pharmacokinetics 59

Drug Patent Watch

FEBRUARY 26, 2025

The Complex World of Biologic Drugs: Navigating Patent Applications As a biotech professional, you're likely no stranger to the intricacies of developing life-changing treatments. But have you ever stopped to think about the patent landscape surrounding biologic drugs? Read the full article here: [link]

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Drug Patent Watch

MARCH 16, 2025

The Biosimilar Revolution: How It's Changing the Game for Biologic Drug Manufacturers As the pharmaceutical industry continues to evolve, one trend is gaining significant attention: the rise of biosimilars. In this article, we'll explore the impact of biosimilars on biologic drug life cycle management.

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Biosimilars Drugs Marketing Pharmaceuticals 52

Drug Hunter

OCTOBER 5, 2023

With initial signs of efficacy and tolerability, Drug Hunter is launching into Phase III! At Drug Hunter, we love structures so much that we forgot to include basic things like headlines and abstracts. With thousands of articles now, many of you have mentioned wanting to see more examples from previous coverage. drughunter.com.

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Trials Drugs 247

Drug Patent Watch

OCTOBER 16, 2024

Biosimilars, which are biologic drugs that are highly similar to an already approved biologic drug, are transforming the pharmaceutical industry. As patents for original biologic drugs expire, biosimilars are becoming increasingly important, offering more affordable treatment options for patients and healthcare systems.

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Drug Patent Watch

JUNE 7, 2022

This article was originally published by Guy Shtar, Louise Azulay, Omer Nizri, Lior Rokach & Bracha Shapira in Scientific Data volume 9, Article number: 263 under a Creative Commons Attribution…. The post CDCDB: A large and continuously updated drug combination database appeared first on DrugPatentWatch - Make Better Decisions.

Drugs 119

Drugs 119

Drug Patent Watch

DECEMBER 30, 2024

The regulatory environment in Japan for generic drug development is complex and has undergone significant changes in recent years. Regulatory Authority: Pharmaceuticals and Medical Devices Agency (PMDA) The PMDA is the primary regulatory authority responsible for overseeing the drug approval process in Japan.

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Drug Development Clinical Pharmacology Clinical Trials Pharmaceutical Companies 52

Chemical Biology and Drug Design

FEBRUARY 15, 2024

Drugs that are currently being used for the management of various types of depression include selective serotonin reuptake inhibitors, tricyclic antidepressants, atypical antidepressants, serotonin, noradrenaline reuptake inhibitors, etc.

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Drugs Research 189

Drug Target Review

APRIL 7, 2025

The challenge of GPCR drug discovery G protein-coupled receptors (GPCRs) are one of the most desirable and challenging target classes in drug discovery, as their mutation can lead to a wide range of diseases such as cancer, cardiovascular disorders and neurological conditions.

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Fragment Screening Drugs Small Molecule Biophysical Assays 52

Drug Patent Watch

JANUARY 15, 2025

Identifying drug patents is crucial for various stakeholders, including researchers, legal professionals, and business strategists. While Google Patents is a widely used tool for searching patent information, it may not be the most effective solution for identifying drug patents. Challenges in Using Google Patents for Drug Patents 1.

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Drugs Pharmaceuticals Engineering Research 59

Drug Patent Watch

OCTOBER 10, 2024

China has emerged as a significant player in the global generic drug active pharmaceutical ingredient (API) market. This article will delve into the role of China in the global generic drug API market, exploring its market share… Source

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Marketing Pharmaceutical Companies Drugs Pharmaceuticals 115

Drug Patent Watch

OCTOBER 14, 2024

Risk assessment plays a crucial role in the development of generic drugs, ensuring that these products meet the required standards of safety and efficacy. This article will delve… Source

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Drug Development Drugs FDA Production 111

Drug Patent Watch

JUNE 20, 2024

In the high-stakes world of pharmaceuticals, patents play a pivotal role in safeguarding intellectual property and ensuring a return on investment for drug developers. The journey of a drug patent is a complex and intricate one, spanning from the initial filing to its eventual expiry.

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Drugs Drug Development Pharmaceuticals 111

Drug Patent Watch

OCTOBER 7, 2024

Pharmacokinetics (PK) plays a crucial role in the development and approval of generic drugs. PK studies help ensure that generic drugs are bioequivalent to their brand-name counterparts, meaning they have similar absorption, distribution, metabolism, and excretion (ADME) profiles.

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Pharmacokinetics Drugs 105

Drug Patent Watch

JUNE 27, 2024

Introduction Patent portfolios are critical assets for pharmaceutical companies, providing market exclusivity and protecting revenue streams for drug products. Effective management of drug patent portfolios requires strategic planning, ongoing evaluation, and adaptation to the evolving pharmaceutical landscape.

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Pharmaceutical Companies Drugs Pharmaceuticals Production 105

Drug Target Review

DECEMBER 20, 2024

Artificial intelligence (AI) has revolutionised many industries, yet its adoption in pharmaceutical drug development has been notably slower. For years, AI and machine learning (ML) were often dismissed as little more than advanced statistics with little practical value in drug development.

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Clinical Trials Trials Pharmaceuticals Drug Development 128

Drug Patent Watch

SEPTEMBER 30, 2024

Patent expirations have a significant impact on the pharmaceutical industry, particularly on the generic drug market. When a drug’s patent expires, other manufacturers can produce and market generic versions of the drug, leading to increased competition and lower prices.

Marketing 105

Marketing Drugs Pharmaceuticals 105

Drug Hunter

MAY 31, 2023

This article compiles 20+ recent small molecules of general interest in the news in April 2023, with structures where they are available. Drug Hunter Premium is drug discovery, distilled, so you can quickly catch up and make informed decisions based on industry examples. Get ahead now by requesting a trial. already a member?

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Small Molecule Clinical Trials Trials Drugs 196

Covalent Modifiers

JANUARY 13, 2024

Thomas Kodadek Angewandte Chemie International Edition 2024 e202316726 [link] Many of the highest priority targets in a wide range of disease states are difficult-to-drug proteins. This article discusses the genesis of the burgeoning field of catalytic inhibitors, the current state of the art, and exciting future directions.

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Small Molecule International Disease Drugs 195

Drug Patent Watch

SEPTEMBER 26, 2024

The generic drug market is a complex and dynamic environment where multiple factors influence the availability, quality, and pricing of generic drugs. This article will discuss the key strategies and… Source

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Marketing Pharmaceutical Companies Drugs Pharmaceuticals 105

Drug Target Review

DECEMBER 6, 2024

In drug discovery and biological research, the scientists workflow often follows a structured and iterative approach to ensure accuracy, reproducibility and scientific integrity. Figure 1: High-level workflow for early drug discovery Once the raw data has been gathered, the next step is to gain a thorough understanding of the data.

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RNA Drugs Research Science 52

Drug Hunter

AUGUST 21, 2023

Obtaining adequate drug exposure in the brain is key to treating CNS diseases effectively. Recently, Dennis Koester gave us a crash course in CNS drug discovery in a Drug Hunter Flash Talk. Why Kp,uu is the Most Important Parameter in CNS Drug Discovery What Influences the Kp,uu of Drugs?

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Drugs Disease Targeted Protein Degradation Screening Hits 206

FDA Law Blog: Drug Discovery

MARCH 19, 2023

s Mark Tobolowsky co-authored the peer-reviewed article “ Microdystrophin Expression as a Surrogate Endpoint for Duchenne Muscular Dystrophy Clinical Trials ” in the recently published edition of Human Gene Therapy. Hyman, Phelps & McNamara, P.C.’s

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Therapies Clinical Trials Treatment Trials 98

Drug Patent Watch

MARCH 17, 2025

The Hidden Costs of Drug Patent Litigation: How to Stay Ahead of the Game As a pharmaceutical professional, you're no stranger to the complexities of drug patent litigation. So, how do you stay ahead of the game when it comes to managing drug patent litigation costs? The stakes are high, and the costs can be astronomical.

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Drugs Pharmaceuticals 52

Drug Patent Watch

SEPTEMBER 18, 2023

The article “Maximizing the Value of Drug Patents Before Losing Exclusivity” discusses strategies for biomedical companies to maximize the value of their drug patents before the exclusivity period expires.

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Drugs 111

Drug Patent Watch

JANUARY 9, 2024

A recent story by NPR echoes the findings of a collaboration between DrugPatentWatch and Bloomberg, which examined increasing competition between generic drug makers. The NPR article discusses the challenges in… The post NPR on how low Drug Prices can Shortages appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs 110

Drug Patent Watch

JANUARY 21, 2025

Mastering the Art of Drug Patent Portfolio Management As a pharmaceutical professional, you know how crucial it is to navigate the complex landscape of drug patents. In our latest blog post, we dive into the best practices for drug patent portfolio management. Read the full article here: [link]

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Drugs Pharmaceutical Companies Pharmaceuticals Marketing 59

Quanticate

AUGUST 2, 2024

Real-world evidence (RWE) is changing clinical drug development, bridging the gap between controlled clinical trial environments and the complexities of everyday patient experiences.

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Drug Development Clinical Trials Drugs Trials 104