Drug Target Review

APRIL 7, 2025

Fragment-based screening (FBS) has emerged as a powerful tool for discovering novel lead compounds, especially for challenging targets like the Adenosine A2a receptor. This crucial role in regulating vital bodily processes makes it a highly important drug target within GPCR research. References Sun D, et al.

Fragment Screening 52

Fragment Screening Drugs Small Molecule Biophysical Assays 52

Molecular Design

JANUARY 12, 2021

In the fourth of his rules for air fighting , ‘Sailor’ Malan (readers may also be interested in his insights into fragment screening library design ) asserts that “height gives you the initiative” which can be adapted for drug design as “affinity gives you the initiative”.

Fragment Screening 52

Fragment Screening Treatment Nurses Doctors 52

Molecular Design

JULY 18, 2020

While I’m not particularly keen on the use of the term ‘open source’ in this context, I have absolutely no quibble with the goal of seeking cures and treatments for diseases that are ignored by commercial drug discovery organizations. by forming a ring). by forming a ring).

Biochemical Assays 52

Biochemical Assays Fragment Screening Pharmacokinetics Drugs 52

PerkinElmer

JUNE 3, 2022

Viral protease inhibitors that block enzymes critical for viral replication have long been used in the treatment of human immunodeficiency (HIV) and hepatitis C viruses. Researchers are now studying the potential of protease inhibitors for the treatment of SARS-CoV-2. For research use only. Not for use in diagnostic procedures.

Fragment Screening 52

Fragment Screening Clinical Trials Vaccine Pharmacokinetics 52