Chemical Biology and Drug Design

JUNE 8, 2023

The co-administration of cryptotanshinone with ophiopogonin D induced pharmacokinetic interaction prolonging the systemic exposure and improving metabolic stability of cryptotanshinone. Abstract Cryptotanshinone and ophiopogonin D are sourced from herbs with similar indications. to 8.58 ± 0.71 μg/mL μg/mL and from 15.99 ± 1.81

Pharmacokinetics 100

Pharmacokinetics Metabolic Stability Research 100

Chemical Biology and Drug Design

SEPTEMBER 20, 2023

Magnoflorine increased the systemic exposure and metabolic stability and suppressed the transport of luteolin. The pharmacokinetic study was performed on male Sprague–Dawley rats randomly grouped as the single administration of luteolin and the co-administration of luteolin and magnoflorine with six rats of each.

Pharmacokinetics 100

Pharmacokinetics Metabolic Stability Regulations Research 100

Molecular Design

MAY 11, 2019

I'll examine an article entitled ‘Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations’ (YL2018) in this post and I should note that the article title reminded me that abseiling has been described as the second fastest way down the mountain.

Metabolic Stability 52

Metabolic Stability Pharmacokinetics Pharmaceuticals Drugs 52