Assay Development Clinical Development Pharmacokinetics 
Drug Discovery World
FEBRUARY 15, 2023
Another widely available commercial model is the cell-line derived xenograft (CDX) 9 that involves inoculation of fast-growing tumour cell lines into immunodeficient mice for various applications including pharmacokinetics, efficacy of cell killing, and studying tumour metastasis by in vivo imaging.
Agency IQ
FEBRUARY 2, 2024
EMA finalizes clinical anticancer therapeutic guidance update In a newly finalized revision, the EMA’s guideline covering all aspects of clinical development of anticancer therapeutics has expanded its already broad scope. The EMA started providing guidance on the clinical development of anticancer therapeutics in 1996.
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