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In 2009, heco-founded the European arm of Essen BioScience, playing a pivotal role in developing industrial-scale, live-cell imaging technology for drug discovery. Previously, he heldsenior director positions at GlaxoSmithKline R&D, leading teams in biological reagents, assaydevelopment, and compound profiling.
Interested in a more disease-focused training for his postdoc, he pursued work in the National Institutes of Health (NIH), particularly in the National Center for Advancing Translational Sciences (NCATS), US. Sam focuses on the application of innovative assaydevelopment strategies to enable to interrogation of complex targets.
We support the drug discovery projects of the CCDD with assaydevelopment and screening, biophysics, structural biology and recombinant protein production. I think as a researcher you have to be honest and transparent about your data, and always do the best science that you possibly can do.
PoLiPa technology Domainex’s Polymer Lipid Particle (PoLiPa) technology offers a versatile, detergent-free platform for the rapid, high-purity preparation of membrane proteins like GPCRs, ion channels and solute carriers, enabling assaydevelopment for these challenging targets.
Christian Soule is the associate director of automation in the Center for the Development of Therapeutics (CDoT) at the Broad Institute of MIT and Harvard, where he leads a team focused on the development and execution of assays for high-throughput screening. Soule holds a B.S. in mechanical engineering from Boston University.
My role involved generating and characterizing complex proteins critical for biological assaydevelopment, hit discovery, and structural biology. During this time, I had the opportunity to step in as an interim Discovery Sciences project lead, sparking my interest in project leadership.
This exciting partnership combines our novel assaydevelopment and hit identification expertise with River BioMedics unique, state-of-the-art technology: advanced human-predictive in vitro 3D heart models, plus their deep knowledge of cardiac biology.
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