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Advancements in screening technologies for small-molecule drug discovery including cellular assays, computational screening, and biophysics-based methods enhanced by structural biology breakthroughs have improved screeninghit rates and facilitated the identification of drug candidates for previously undruggable targets.
The team that I lead within the CCDD is called the Hit Discovery and Structural Design Team. We support the drug discovery projects of the CCDD with assaydevelopment and screening, biophysics, structural biology and recombinant protein production. Although we are an academic centre we work very much like industry.
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