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Accelerating Medicinal Chemistry Cycle Times Through Cloud-Accessible Smart Automated Labs - A Preview of Strateos’ Presentation at SLAS 2022

The Strateos Blog: Drug Discovery

Progress from target ID through to IND submission in conventional workflows can take upwards of 6+ years, where success hinges on iterative cycles of DMTA.

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Top 10 Drug Discovery Trends at the Top 20 Pharma

PerkinElmer

Small screens are better than large ones. Biochemical assays have the highest success rate. Small molecules are making a comeback. For the minority of companies working with large molecules and biologics, most said they were in a phase of clinical research. Biologics are booming. Think again.

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Are fused tetrahydroquinolines interfering with your assay?

Molecular Design

I’ll start with the significance section and my comments are italicized in red: Tricyclic tetrahydroquinolines (THQs) are a family of lesser studied pan-assay interference compounds (PAINS) [The authors need to provide specific examples of tricyclic THQs that have been actually been shown to exhibit pan-assay interference to support this claim.]