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High Throughput Screening (HTS)

Sygnature Discovery

Compounds are drug-like with high chirality and FSP3 and the library contains novel natural product inspired scaffolds. Collaboration with customers and Sygnatures computational chemists ensures quality hit identification using computational chemistry triage, counter screens, and orthogonal assays.

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Target-directed cancer: protein-ligand interactions  

Drug Target Review

We support the drug discovery projects of the CCDD with assay development and screening, biophysics, structural biology and recombinant protein production. For example, in the screening stage of a project we are trying to find initial starting points for optimisation by our medicinal and computational chemistry colleagues.