Drug Target Review

JULY 12, 2023

Molecular-level biochemical assays like transcriptomics, genomics and proteomics have emerged as valuable tools for identifying potential targets in cancer treatment through deep cyclic inhibition (DCI). We are pleased that to date our lead product candidate has aligned DCI profiles as expected.

Biochemical Assays 98

Biochemical Assays Treatment Bioinformatics Disease 98

Drug Target Review

NOVEMBER 1, 2023

The mission of the CCDD is to discover novel small-molecule therapeutics for the treatment of cancer and progress them to hypothesis testing phase 1 clinical trials. We support the drug discovery projects of the CCDD with assay development and screening, biophysics, structural biology and recombinant protein production.

Fragment Screening 96

Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96

The Strateos Blog: Drug Discovery

DECEMBER 13, 2021

Progress from target ID through to IND submission in conventional workflows can take upwards of 6+ years, where success hinges on iterative cycles of DMTA.

Biochemical Assays 52

Biochemical Assays Small Molecule Laboratories Science 52

PerkinElmer

FEBRUARY 18, 2021

Small screens are better than large ones. Biochemical assays have the highest success rate. Dr. Eckelt conducted 23 hour-long, 1:1 interviews over five months in 2020 to gather market insights on how the top 20 Pharma are increasing productivity, efficiency, and speed of drug discovery in the short and long-term.

Biochemical Assays 52

Biochemical Assays Drugs Small Molecule Pharma Companies 52

Drug Target Review

JANUARY 5, 2024

6 Conventionally, heterotrimeric G protein alpha (Ga) subunits connect agonist-activated G protein-coupled receptors (GPCRs) to intracellular changes in second messenger production ( Figure 1a ). 7 In contrast to this conventional Ga protein biochemical behaviour, the authors found that two of the thirteen identified N.

Small Molecule 59

Small Molecule Drugs Biochemical Assays Regulations 59