Drug Target Review

JULY 12, 2023

Molecular-level biochemical assays like transcriptomics, genomics and proteomics have emerged as valuable tools for identifying potential targets in cancer treatment through deep cyclic inhibition (DCI). Author Bio: Brett Hall Brett has been Chief Scientific Officer at Immuneering since November 2019.

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Biochemical Assays Treatment Bioinformatics Disease 98

Drug Target Review

NOVEMBER 1, 2023

The mission of the CCDD is to discover novel small-molecule therapeutics for the treatment of cancer and progress them to hypothesis testing phase 1 clinical trials. We often screen using a biochemical assay, but we can conduct cell-based screening as well. We need to build the assays that we need for compound screening.

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Fragment Screening Biochemical Assays Small Molecule Biophysical Assays 96

The Strateos Blog: Drug Discovery

DECEMBER 13, 2021

SLAS 2022 is set to be an exciting conference where scientists can come together to learn about the innovative technologies transforming the way life sciences research is executed. Progress from target ID through to IND submission in conventional workflows can take upwards of 6+ years, where success hinges on iterative cycles of DMTA.

Biochemical Assays 52

Biochemical Assays Small Molecule Laboratories Science 52

PerkinElmer

FEBRUARY 18, 2021

Small screens are better than large ones. Biochemical assays have the highest success rate. Small molecules are making a comeback. For the minority of companies working with large molecules and biologics, most said they were in a phase of clinical research. Biologics are booming. Think again.

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Biochemical Assays Drugs Small Molecule Pharma Companies 52

Drug Target Review

JANUARY 5, 2024

Å resolution) 6 is now being targeted for small molecule inhibitor discovery and development, by exploiting emergent computational tools to identify potential candidate compounds in silico and then test these predicted inhibitors in in vitro biochemical assays. Thousand Oaks, CA) in 1999 before returning to academia.

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Small Molecule Drugs Biochemical Assays Regulations 59