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Bile acids and the microbiome: revolutionising disease approaches

Drug Target Review

For example, bile acid treatments have been effective against SARS-Cov-2 infections. Bile acids and bile activated receptors in the treatment of Covid-19. Biochemical Pharmacology. Gut Microbes. 2023 February 5 [2024 March 11]; 15(1). Available from: [link] 2 Biagoli M, Distrutti E, Fiorucci S, et al.

Disease 111
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Targeting the immunotherapy potential of cytokines IL-12 and IL-18 with new advancements in protein engineering

Drug Target Review

In this IO arena, we continue to search for additional treatments that can further benefit patients. Immune checkpoint inhibitors, a well-established class of IO treatments, are designed to improve the ability of T-cells to fight cancer by removing inhibitory or suppressive mechanisms that may dampen the anti-cancer functions of T cells.