Bioinformatics, Clinical Development and Immune Response

Not all neoantigens are created equal

Drug Target Review

DECEMBER 28, 2023

These neoantigens are identified by T cells of the immune system as foreign proteins and thus trigger an immune response. Recent advances in bioinformatics show clonal neoantigens are the best targets for immunotherapy, as I will elucidate below. Neoantigens are recognised as non-self and trigger an immune response.

Bioinformatics

Bioinformatics Immune Response DNA Vaccine

The first major set of genetic associations found in long COVID

Drug Target Review

DECEMBER 13, 2023

The genes unique to the severe long COVID patients were found to be associated with immune pathways such as myeloid differentiation, macrophage foam cells and lipid signalling pathways. Can you elaborate on how these antagonists may help with long COVID?

Bioinformatics

Bioinformatics Disease Regulations Immune Response

Drug Discovery Digest

Not all neoantigens are created equal

The first major set of genetic associations found in long COVID

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