Practical Cheminformatics

JANUARY 16, 2024

Following up on Part I and Part II, the third post in this series is a collection of review articles published in 2023 that I found helpful.

Targeted Protein Degradation 141

Targeted Protein Degradation Small Molecule Computational Chemistry Bioinformatics 141

Drug Discovery World

SEPTEMBER 9, 2024

The transformative power of AI While Foundation Models (FMs), including Large Language Models (LLMs) and image-based models, may not exhibit true intelligence, their potential to revolutionise fields like drug discovery and materials science is undeniable. Small Language Models (SLMs) are gaining traction, particularly in the life sciences.

Drugs 162

Drugs Bioinformatics Computational Chemistry International 162

Drug Discovery World

NOVEMBER 8, 2023

Kathrin Herbst, PhD, Director of Science & Business Development, Lightcast, on: ‘A new era of single-cell functional profiling for drug discovery’. David Mills, PhD, Senior Director, Preclinical Science, Ambrx, on: ‘Preclinical discovery of ARX622, a site-specific HER2-targeted TLR7 agonist immune-stimulatory antibody conjugate’.

Engineering 162

Engineering Protein Expression Therapies Science 162

The Pharma Data

NOVEMBER 15, 2020

Our rigorous target selection process, translational screening cascade, and smart medicinal chemistry have been essential to bring this project to this stage. Lead Pharma is headquartered at Pivot Park, the biopharmaceutical life sciences campus in Oss, the Netherlands. ” About Immune Mediated Diseases.

Small Molecule 52

Small Molecule Licensing Licensing Disease 52

Dark Matter Blog

AUGUST 31, 2020

Emblematic of Arrakis’ collaborative approach to science, almost all of the scientists in the lab—or, in the case of our colleagues in computational chemistry and biology, on their computers—at the time contributed to developing the PEARL-seq platform. With any luck, we’ll figure out our landing gear next.

RNA 52

RNA Small Molecule Bioinformatics Computational Chemistry 52