Practical Cheminformatics

JANUARY 16, 2024

Property Prediction Machine Learning Methods for Small Data Challenges in Molecular Science [link] Practical guidelines for the use of gradient boosting for molecular property prediction [link] Application of message passing neural networks for molecular property prediction [link] Molecular Similarity Molecular Similarity: Theory, Applications, and (..)

Targeted Protein Degradation 141

Targeted Protein Degradation Small Molecule Computational Chemistry Bioinformatics 141

Drug Discovery World

SEPTEMBER 9, 2024

This capability enables their use in various bioinformatics and cheminformatics applications, including predicting DNA regulatory elements and optimising drug properties. Dr Dogruel has a PhD in Bioinformatics from the University of Cambridge.

Drugs 162

Drugs Bioinformatics Computational Chemistry International 162

The Pharma Data

NOVEMBER 15, 2020

R&D collaboration building on Lead Pharma’s expertise in the discovery, design and optimization of small molecule treatments. Lead Pharma may receive payments of up to €260 million plus royalties on sales. OSS, Netherlands , Nov. OSS, Netherlands , Nov.

Small Molecule 52

Small Molecule Licensing Licensing Disease 52

Dark Matter Blog

AUGUST 31, 2020

The majority of small molecule drugs induce their therapeutic effects by seeking out and binding to their intended target while avoiding most other molecules in the dense milieu of the cell interior. Our overall mission at Arrakis is to expand the set of “druggable” targets for small-molecule medicines to include RNA.

RNA 52

RNA Small Molecule Bioinformatics Computational Chemistry 52