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AI in Drug Discovery - A Highly Opinionated Literature Review (Part II)

Practical Cheminformatics

Picking up where we left off in Part I , this post covers several other ML in drug discovery topics that interested me in 2023. Aside from some very brief demos on code generation and literature searches, mentions of LLM applications in preclinical research were scarce. Most of the drug discovery examples were underwhelming.

Drugs 141
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Is That DNA Dangerous?

Codon

5 But it could match up to one of the threats in your reference database, so you opt to throw a battery of bioinformatics tools at it. BLAST is covered in every introductory bioinformatics course and the 1990 paper introducing has over 110,000 citations. Bioinformatic results from SecureDNA. Bioinformatic results from HMMScan.

DNA 80