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Big data – charting a new path to drug discovery and development

Drug Discovery World

Now, with the growth of publicly available genomics, transcriptomics, and proteomics databases, the ability to quickly carry out large-scale DNA, RNA, and protein screenings, and the availability of massive sets of de-identified patient data, the amount of high-value, analysable data has reached enormous proportions.

Science 100
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Is That DNA Dangerous?

Codon

Tessa Alexanian and Max Langenkamp build computational DNA screening tools for a living. A concerned employee at a laboratory supply company had called the Centers for Disease Control, or CDC, after fielding repeated calls from Harris asking when his samples of plague would arrive in the mail. This article concludes our mini-issue.

DNA 80
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Synthetic biology tools advancing and accelerating drug discovery efforts

Drug Discovery World

It has made its way into almost every aspect of drug discovery, whether it’s exploring basic biology, modelling diseases, identifying and validating targets, or performing drug screens. . Rapid and accurate DNA synthesis . Issues with DNA fidelity, therefore, limit the maximum sequence length to ~300 base pairs.

DNA 246
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A scientist devotes her career to tackling inequity in genomics

Broad Institute

Credit: Allison Colorado, Broad Communications Arriving in the Bay Area after a childhood in increasingly diverse surroundings, Martin became acutely aware of health disparities and the profound differences in disease prevalence among different populations. I wanted to know how I could have any impact on studying genetic diversity.”