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Six scientists named as new core institute members at Broad

Broad Institute

At the Broad, he directs the Cancer Genome Computational Analysis Group , and he is a professor of pathology at Harvard Medical School and director of bioinformatics at Massachusetts General Hospital. She also leads Broad’s rare disease initiative, Ladders to Cures.

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Not all neoantigens are created equal

Drug Target Review

Recent advances in bioinformatics show clonal neoantigens are the best targets for immunotherapy, as I will elucidate below. Patients with high numbers of clonal neoantigens show improved disease-free survival. These mutations are called clonal mutations or clonal neoantigens.

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A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic

Broad Institute

He started to imagine how the deadly and contagious disease, if confirmed, might spread to half the city’s population. Eight of the 20 patients died, but the spread of the disease in Nigeria stopped there. Blood and urine samples from the man were waiting for Happi in his lab. Happi felt chilled. They called the idea Sentinel.

Virus 132
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The use-case for NGS

Drug Discovery World

DDW Editor Reece Armstrong speaks to Dr Darrell Green , Lecturer in RNA Biology Biomedical Research Centre Norwich Medical School University of East Anglia, about his work using next generation sequencing (NGS) and the areas the technology is impacting within drug discovery and development.

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A scientist devotes her career to tackling inequity in genomics

Broad Institute

Credit: Allison Colorado, Broad Communications Arriving in the Bay Area after a childhood in increasingly diverse surroundings, Martin became acutely aware of health disparities and the profound differences in disease prevalence among different populations. I wanted to know how I could have any impact on studying genetic diversity.”

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Molecular map reveals insights into the genetic drivers of chronic lymphocytic leukemia

Broad Institute

By Tracy Hampton August 4, 2022 Credit: National Institutes of Allergy and Infectious Diseases, National Institutes of Health Colorized scanning electron micrograph of a B cell lymphocyte from a human donor.