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Not all neoantigens are created equal

Drug Target Review

During the process of transformation from a normal cell into a cancer cell, a cell acquires a series of changes, or mutations, in its DNA. But DNA mutations can also result in changes to the proteins that are displayed on the surface of the cancer cell. These mutations are called clonal mutations or clonal neoantigens.

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Twist Bioscience Harnesses AI-Powered Cloud for Synthetic Biology Breakthroughs

Fierce BioTech

The company has developed a disruptive DNA synthesis platform that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip. Listing Image oracle Listing Introduction Twist Bioscience’s DNA-based products are powering research to improve the lives of millions of people.

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Boehringer Ingelheim and Twist Bioscience Enter Therapeutic Antibody Discovery Collaboration

The Pharma Data

By leveraging our unique ability to manufacture DNA at scale, we can construct proprietary antibody libraries precisely designed to match sequences that occur in the human body. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip.

DNA 52
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A quiet revolution in the world of proteomics

DrugBaron

For example, thrombin is generated by the cleavage of prothrombin by the prothrombinase complex; C3b the “engine” of the complement response is generated by the cleavage of C3 by enzymes such as complement factor B. Yet most modern proteomic protocols cannot readily distinguish thrombin from prothrombin or C3b from C3.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. Known as a "search-and-replace" gene-editing tool, prime editors can delete or replace DNA up to 10,000 bases in length, or substitute one base for another. Read more in Cell. ( #1 , #2 ) (Video credit: Gong Y.

DNA 52
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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. Known as a "search-and-replace" gene-editing tool, prime editors can delete or replace DNA up to 10,000 bases in length, or substitute one base for another. Read more in Cell. ( #1 , #2 ) (Video credit: Gong Y.

DNA 52
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Scientists discover new antiviral defense system in bacteria

Broad Institute

It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.” “It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.”

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