The Pharma Data

SEPTEMBER 11, 2021

By leveraging our unique ability to manufacture DNA at scale, we can construct proprietary antibody libraries precisely designed to match sequences that occur in the human body. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip.

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DNA Bioinformatics Production Engineering 52

Drug Discovery World

NOVEMBER 15, 2022

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. Rapid and accurate DNA synthesis .

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DNA Engineering Drugs Vaccine 246

Drug Discovery World

JULY 26, 2023

This leap in understanding, which has been facilitated by the emergence of next generation sequencing (NGS) technologies and bioinformatics tools such as artificial intelligence (AI), has brought forward a new wave of precision medicine resources, diagnostics, and therapeutics specifically aiming to leverage the microbiome.

Bioinformatics 130

Bioinformatics Clinical Trials DNA Disease 130

Drug Discovery World

NOVEMBER 9, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’.

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Engineering Therapies Protein Production Science 130

Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

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Clinical Trials Research Science Clinical Research 130

Drug Discovery World

NOVEMBER 13, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Ali Madani, PhD, Founder and CEO, Profluent Bio, on: ‘Protein engineering with large language models’.

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Engineering Science Bioinformatics Vaccine 147

Drug Discovery World

SEPTEMBER 7, 2022

Many companies have embarked on a digitalisation journey, convinced that their notebook entries, DNA and protein designs, samples used in experiments, and experimental conditions should all be tracked and stored in software. If all the work scientists do is captured in software, it ought to be easier to analyse. .

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Drug Discovery World

NOVEMBER 30, 2023

Sphere Fluidics presence on the exhibition floor was bolstered by a presentation from Richard Hammond: ‘Picodroplets for cell Line engineering: A novel automation approach’. It was presented by Xiaole Shirley Liu, PhD, CEO, GV20 Therapeutics, and titled: ‘AI-based target and antibody discovery from patient tumour profiles’.

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Protein Expression Engineering DNA Therapies 147

The Open Targets Blog

APRIL 25, 2023

Although the estate was undoubtedly pretty, the Hall had seen better days and was rather dominated by a 1950s building that provided laboratories for the light engineering company that had owned the site. ranging from university academics through engineers and clerical staff to the military. The same went for analysis tools.

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Codon

MAY 15, 2023

3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. Known as a "search-and-replace" gene-editing tool, prime editors can delete or replace DNA up to 10,000 bases in length, or substitute one base for another. Read more in Cell. ( #1 , #2 ) (Video credit: Gong Y.

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DNA Bioinformatics Engineering Virus 52

Codon

MAY 15, 2023

3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. Known as a "search-and-replace" gene-editing tool, prime editors can delete or replace DNA up to 10,000 bases in length, or substitute one base for another. Read more in Cell. ( #1 , #2 ) (Video credit: Gong Y.

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DNA Bioinformatics Engineering Virus 52

Broad Institute

AUGUST 11, 2022

It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.” “It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.”

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DNA Virus Immune Response Bioinformatics 52

Elrig

APRIL 29, 2024

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. Bioinformatics is all about bringing together different areas of knowledge. Do you think the current talent pool supply meets the demand?

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Bioinformatics Molecular Biology Drugs Cell Based Assays 59

Dark Matter Blog

AUGUST 31, 2020

The initial discussions that would lead to the PEARL-seq platform involved scanning the literature for the wings, propellers, and engines that we thought we could use. We stuck with our trusty aptamer system, but instead of running the DNA products made by RT on a gel, we attached them to adapters that enabled next-generation sequencing.

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RNA Small Molecule Bioinformatics Computational Chemistry 52

Vial

DECEMBER 5, 2023

Transforming Genomics Research Next-generation sequencing (NGS) enables comprehensive genome sequencing and has transformed genomics research, offering vastly improved capabilities for analyzing DNA and RNA in a high-throughput and cost-effective manner. Satam et al. Let’s Connect.

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Clinical Trials Trials RNA Bioinformatics 52

DrugBaron

NOVEMBER 22, 2022

For example, thrombin is generated by the cleavage of prothrombin by the prothrombinase complex; C3b the “engine” of the complement response is generated by the cleavage of C3 by enzymes such as complement factor B. Yet most modern proteomic protocols cannot readily distinguish thrombin from prothrombin or C3b from C3.

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Bioinformatics Regulations Molecular Biology Engineering 100

Codon

AUGUST 10, 2023

Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. ” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J.

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DNA Cell Biology Molecular Biology Engineering 93

Codon

AUGUST 10, 2023

Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. ” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

Codon

APRIL 16, 2023

Codon Digest is my weekly roundup of research, news, and industry highlights about engineered biology. These microbes were engineered to express tumor antigens that could “elicit T cells that were licensed by the commensal immune program but specific for a tumor,” including both CD4+ and CD8+ T cells, according to the study.

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Engineering DNA RNA Science 52