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Not all neoantigens are created equal

Drug Target Review

During the process of transformation from a normal cell into a cancer cell, a cell acquires a series of changes, or mutations, in its DNA. But DNA mutations can also result in changes to the proteins that are displayed on the surface of the cancer cell. These mutations are called clonal mutations or clonal neoantigens.

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Twist Bioscience Harnesses AI-Powered Cloud for Synthetic Biology Breakthroughs

Fierce BioTech

The company has developed a disruptive DNA synthesis platform that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip. Listing Image oracle Listing Introduction Twist Bioscience’s DNA-based products are powering research to improve the lives of millions of people.

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Malaria unravelled: decoding the parasite’s gene expression control

Drug Target Review

Researchers from Tokyo Tech’s World Research Hub Initiative conducted a study to investigate the regulation of gene expression in the apicoplast of the malaria parasite Plasmodium falciparum. He has shared his excitement about the study’s implications and how it opens up new avenues in malaria research.

RNA 98
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Defense-Forward Biosecurity

Codon

Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.

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A scientist devotes her career to tackling inequity in genomics

Broad Institute

Thanks in part to her research, more geneticists are now studying a wider diversity of people and accounting for genetic ancestry in their analyses. Through this work, Martin is showing how a methodical, data-driven kind of social justice can help improve equity in scientific research and lead to better science.

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Boehringer Ingelheim and Twist Bioscience Enter Therapeutic Antibody Discovery Collaboration

The Pharma Data

Senior Corporate Vice President and Global Head of Discovery Research at Boehringer Ingelheim. “We Twist and Boehringer Ingelheim will work together to validate and optimize any resulting new antibody candidates, which could be researched against a range of therapeutic areas. Wood, Ph.D., Leproust, Ph.D., CEO and co-founder of Twist.

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Kickstarting the use of AI for biotechs: part two

Drug Target Review

2 AlphaFold 3 has been built to model DNA, RNA and smaller molecules (ligands). 5 Several major technology areas are not included above, such as cheminformatics and bioinformatics. Google DeepMind’s new AI can model DNA, RNA, and ‘all life’s molecules’. The latest exciting advancement is AlphaFold 3, which was just released.

RNA 59