Remove Bioinformatics Remove DNA Remove RNA
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Reaching cruising altitude: New discovery tools to target RNA

Dark Matter Blog

Our overall mission at Arrakis is to expand the set of “druggable” targets for small-molecule medicines to include RNA. Today, we are pleased to announce that our article describing one such platform: “ PEARL-seq, A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions ” was published in ACS Chemical Biology.

RNA 52
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Can Global Genomic Surveillance Forecast the Next Pandemic?

PLOS: DNA Science

Many of the links below are to some of the 100+ DNA Science posts that I wrote during the pandemic. As soon as the initial RNA genome sequence of the pathogen that would be named SARS-CoV-2 was published, CDC and other organizations began developing diagnostic tests. appeared first on DNA Science. Work on vaccines ensued too.

Virus 98
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Malaria unravelled: decoding the parasite’s gene expression control

Drug Target Review

Through phylogenetic analysis and microscopy techniques, they identified a nuclear-encoded apicoplast RNA polymerase σ subunit called ApSigma. The initial subject of my research carrier was RNA polymerase principal sigma factors in bacteria. The first identification was based on a bioinformatic analysis.

RNA 98
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Next Generation Sequencing (NGS): why is quantifying nucleic acids important? | BMG LABTECH

BMG Labtech

These numbers reflect impressive developments in DNA sequencing technologies but in most cases represent the immediate costs of consumables on the sequencing instrument. 2 DNA sequencing is also reliant on sample processing and DNA library preparation before sequencing as well as bioinformatics and data analysis after sequencing.

DNA 52
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Kickstarting the use of AI for biotechs: part two

Drug Target Review

2 AlphaFold 3 has been built to model DNA, RNA and smaller molecules (ligands). 5 Several major technology areas are not included above, such as cheminformatics and bioinformatics. Google DeepMind’s new AI can model DNA, RNA, and ‘all life’s molecules’. Alphafold 3.0: the AI protein predictor gets an upgrade.

RNA 59
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Defense-Forward Biosecurity

Codon

Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.

DNA 81
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Next Generation Sequencing (NGS) in Clinical Trials: Challenges and Opportunities

Vial

Transforming Genomics Research Next-generation sequencing (NGS) enables comprehensive genome sequencing and has transformed genomics research, offering vastly improved capabilities for analyzing DNA and RNA in a high-throughput and cost-effective manner. Satam et al.