Codon

AUGUST 28, 2024

Tessa Alexanian and Max Langenkamp build computational DNA screening tools for a living. But today, rapid advances in DNA synthesis have made it possible for would-be bioterrorists to make pathogens, rather than buy them. National Science Advisory Board for Biosecurity urged the U.S. This article concludes our mini-issue.

DNA 85

DNA Bioinformatics Virus Government 85

Drug Discovery World

JULY 11, 2023

Tim Lowery , President, JSR Life Sciences, asks whether artificial intelligence can do for life sciences what it has done in other sectors and whether these tools can keep up with the complexities of human biology. So, where do we go from here to realise their potential in life sciences?

Science 100

Science Drugs FDA Engineering 100

Drug Target Review

JULY 24, 2023

The results were published in Proceedings of National Academy of Sciences of United States of America (PNAS). The first identification was based on a bioinformatic analysis. Author Bio: Kan Tanaka Kan Tanaka, PhD has worked as Professor, Laboratory for Chemistry and Life Science at the Tokyo Institute of Technology since 2016.

RNA 98

RNA Regulations Bioinformatics Laboratories 98

Drug Discovery World

APRIL 14, 2023

Carolyn R Bertozzi, PhD – Outstanding Achievement in Chemistry in Cancer Research Bertozzi is the Baker Family Director of Sarafan ChEM-H, the Anne T and Robert M Bass Professor in the School of Humanities and Sciences, Professor of Chemistry and, by courtesy, of Chemical and Systems Biology and of Radiology at Stanford University.

Clinical Trials 130

Clinical Trials Research Science Clinical Research 130

Drug Discovery World

NOVEMBER 15, 2022

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. Rapid and accurate DNA synthesis .

DNA 246

DNA Engineering Drugs Vaccine 246

Drug Discovery World

OCTOBER 25, 2023

However, the ligation step is biased and inefficient because the enzymes that ligate the adapters, which are DNA and RNA sequences, prefer some sRNAs that the adapters are ligated to. RA: How accessible have NGS technologies become for life sciences researchers? Plus, this will be for any genetic disorder, not just cancer.

Bioinformatics 287

Bioinformatics Pharmacogenetics RNA Medical Schools 287

Drug Discovery World

APRIL 29, 2024

Dr Andrew Lewis, Chief Scientific Officer; Kieron Hall, Chief Marketing Officer; and Eric Bironneau, Chief Business Officer, Quotient Sciences: Lewis has held various scientific leadership positions at Quotient and was previously Director of Novel Drug Delivery Technologies at Ipsen.

Drugs 130

Drugs Small Molecule Bioinformatics Pharmaceuticals 130

Drug Discovery World

SEPTEMBER 7, 2022

In 2018, the CEO of Novartis declared that Novartis would become a data science company. A year later, he discussed the challenges of powering their R&D with data science and the need for good, clean data. . Why is this such a challenge in life sciences? However, there are challenges with this approach.

Science 130

Science DNA Bioinformatics Engineering 130

PLOS: DNA Science

MAY 16, 2024

These factors are converging to enable both identification of novel infectious diseases as well as microbial resistance, before these threats can impact public health, write a team from the European Society for Clinical Microbiology and Infectious Diseases in Frontiers in Science. It closed a year ago. . • Single-cell sequencing.

Virus 82

Virus DNA RNA Vaccine 82

Drug Discovery World

NOVEMBER 13, 2023

Enkelejda Miho, PhD, Professor, University of Applied Sciences and Arts Northwestern Switzerland, and Managing Director, aiNET, on: ‘The singular immune response to dengue and machine learning identification of antibodies in high-throughput sequences’.

Engineering 147

Engineering Science Bioinformatics Vaccine 147

Drug Discovery World

NOVEMBER 9, 2023

Peter O’Callaghan, PhD, Head of Expression System Sciences, Biologics and Licensing, Lonza, on: ‘Solve bispecific heavy-light chain mispairing with bYlok technology’. Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’.

Engineering 130

Engineering Therapies Protein Production Science 130

Elrig

APRIL 29, 2024

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. Rising from Research Scientist to Senior Scientist, I supported early-stage DD efforts within their Protein Science group, based in Cambridge, UK.

Bioinformatics 59

Bioinformatics Molecular Biology Drugs Cell Based Assays 59

Broad Institute

AUGUST 11, 2022

The study appears in Science. It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.” Most known bacterial defense systems work by sensing viral DNA or RNA, or cellular stress due to the infection.

DNA 52

DNA Virus Immune Response Bioinformatics 52

Drug Discovery World

NOVEMBER 30, 2023

The next presentation attended in this track was the keynote presentation, which was given by Kate Smith, PhD, Head of UK Protein & Cell Sciences at GSK. Lightcast is developing a novel, programmable microfluidic platform that allows precise and highly flexible control of individual microdroplets using software-generated light patterns.

Protein Expression 147

Protein Expression Engineering DNA Therapies 147

Codon

MAY 15, 2023

Every science journalist under the sun has covered this paper (though I recommend Ed Yong’s ). 3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. PE-tag is a new method that detects off-target DNA changes during a gene-editing experiment. From Davis J.R.

DNA 52

DNA Bioinformatics Engineering Virus 52

Codon

MAY 15, 2023

Every science journalist under the sun has covered this paper (though I recommend Ed Yong’s ). 3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. PE-tag is a new method that detects off-target DNA changes during a gene-editing experiment. From Davis J.R.

DNA 52

DNA Bioinformatics Engineering Virus 52

Drug Discovery World

APRIL 14, 2023

Whilst the cause of DIPG isn’t known, the disease is characterised by specific mutations in genes coding for histone proteins – a family of basic proteins which can associate with DNA due to their positive charges. BMC Bioinformatics. These mutated proteins then reprogramme the epigenome, from which the cancer develops.

DNA 130

DNA Disease Bioinformatics Research 130

Dark Matter Blog

AUGUST 31, 2020

Emblematic of Arrakis’ collaborative approach to science, almost all of the scientists in the lab—or, in the case of our colleagues in computational chemistry and biology, on their computers—at the time contributed to developing the PEARL-seq platform. Our expedition gains altitude After that initial result, it was all hands on deck.

RNA 52

RNA Small Molecule Bioinformatics Computational Chemistry 52

Broad Institute

JULY 10, 2023

Through this work, Martin is showing how a methodical, data-driven kind of social justice can help improve equity in scientific research and lead to better science. Scientists calculate these scores for a population by comparing millions of single-letter changes in the DNA of large groups of people with and without a disease or trait.

Bioinformatics 98

Bioinformatics Disease Medical Schools Research 98

The Open Targets Blog

APRIL 25, 2023

However, there are notable parallels both in the way the science was conducted and, at least for the genome project in the UK, the particular physical settings and sensibilities. Bioinformatics, Volume 13, Issue 4, August 1997, Pages 333–344 9. Now I don’t want to claim too much. Left: Bletchley Park, photo by Einar H.

DNA 52

DNA Government Engineering Laboratories 52

The Pharma Data

JANUARY 10, 2021

NantWorks and ImmunityBio Chief Executive Officer, Patrick Soon-Shiong , believes that science has reached the point where it is ready to pit a “triangle offense” against even the toughest cancers. A Whole New ‘Science Matters’ Perspective . “I And then, always, ‘science matters.’ Read on for more. .

Vaccine 52

Vaccine Regulations Disease Small Molecule 52

The Pharma Data

MARCH 20, 2021

Bioinformatics in the Faculty. of Medicine and Health Sciences (Ghent University) and. DNA biomarker services in an accredited environment. Vandesompele is a research. professor in Functional Cancer Genomics and Applied. also the co-founder and CSO of. Biogazelle, an innovative bioanalytical services company offering RNA and.

Laboratories 52

Laboratories Virus RNA Bioinformatics 52

Codon

AUGUST 10, 2023

Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Link DNA synthesis technologies to close the gene writing gap , by Hoose et al.

DNA 93

DNA Cell Biology Molecular Biology Engineering 93

Codon

AUGUST 10, 2023

Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link DNA Cost and Productivity Data, aka "Carlson Curves" , by Carlson R. Link Next-Generation DNA Sequencing Methods , by Mardis E.R. Link DNA synthesis technologies to close the gene writing gap , by Hoose et al.

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

Codon

APRIL 16, 2023

Short DNA strands were discovered that can specifically and tightly bind to zinc and cadmium ions. Perhaps there is now a way to use DNA to extract metals: You could fuse the DNA strands to an antibody, coat them onto electronics, and then use a column to isolate the DNA:metal compounds? BMC Bioinformatics. Kesner J.S.

Engineering 52

Engineering DNA RNA Science 52