Remove Bioinformatics Remove DNA Remove Vaccine
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Not all neoantigens are created equal

Drug Target Review

During the process of transformation from a normal cell into a cancer cell, a cell acquires a series of changes, or mutations, in its DNA. But DNA mutations can also result in changes to the proteins that are displayed on the surface of the cancer cell. These mutations are called clonal mutations or clonal neoantigens.

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Can Global Genomic Surveillance Forecast the Next Pandemic?

PLOS: DNA Science

Had we grown complacent in a world freed from a list of once-deadly infectious diseases, thanks largely to vaccines and other public health measures? Many of the links below are to some of the 100+ DNA Science posts that I wrote during the pandemic. Work on vaccines ensued too. COVID clearly caught us off guard.

Virus 98
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Defense-Forward Biosecurity

Codon

Allison Berke makes the case for real-time DNA sequencing and AI tools to detect pathogens before they spread widely. Reading DNA The first step in detecting a novel pathogen is recognizing it as an anomaly amidst a noisy background of other material. After copying the DNA to form a big pool, each piece is sequenced.

DNA 102
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A quiet revolution in the world of proteomics

DrugBaron

It incorporates a number of different technological advances both in the practical LC-MS data collection and in the subsequent bioinformatic analysis developed by Methuselah Health over the last decade. This can be useful to quantify protein adducts (for example when radiolabelling a protein or preparing antigens for vaccine production).

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. Known as a "search-and-replace" gene-editing tool, prime editors can delete or replace DNA up to 10,000 bases in length, or substitute one base for another. Read more in Cell. ( #1 , #2 ) (Video credit: Gong Y.

DNA 52
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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

3/ Prime Editing Spree Prime editors can change DNA in ways that Cas9 — and even base editors — cannot. Known as a "search-and-replace" gene-editing tool, prime editors can delete or replace DNA up to 10,000 bases in length, or substitute one base for another. Read more in Cell. ( #1 , #2 ) (Video credit: Gong Y.

DNA 52
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Tackling the Challenges of Limited Resources During a Pandemic

The Pharma Data

Bioinformatics in the Faculty. DNA biomarker services in an accredited environment. effective SARS-CoV-2 vaccine continues to attract. Vandesompele is a research. professor in Functional Cancer Genomics and Applied. of Medicine and Health Sciences (Ghent University) and. also the co-founder and CSO of. samples per day.