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Not all neoantigens are created equal

Drug Target Review

These neoantigens are identified by T cells of the immune system as foreign proteins and thus trigger an immune response. Recent advances in bioinformatics show clonal neoantigens are the best targets for immunotherapy, as I will elucidate below. Neoantigens are recognised as non-self and trigger an immune response.

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The first major set of genetic associations found in long COVID

Drug Target Review

The genes unique to the severe long COVID patients were found to be associated with immune pathways such as myeloid differentiation, macrophage foam cells and lipid signalling pathways. She is a computational biologist with a background in bioprocess engineering and biotechnology.

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Defense-Forward Biosecurity

Codon

Doctors in training are told that when they hear hoofbeats, they should think horses, not zebras; rare diseases are the exception, not the rule. For example, many different filoviruses attack white blood cells and cause similar innate immune responses , which makes it difficult to identify a particular species from only their DNA.

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