Drug Target Review

AUGUST 11, 2023

1 The study reveals a novel bioinformatic approach and tool that holds the potential to empower researchers in designing vaccines capable of inducing a stronger immune response. By honing in on these critical regions, vaccines can be engineered to prompt a more potent and targeted defence against infectious pathogens.

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Fierce BioTech

OCTOBER 26, 2023

They turned to Oracle Cloud Infrastructure to quickly deploy, optimize, and scale a bioinformatics pipeline for predicting protein structures in drug discovery efforts, as well as accelerate the adoption of a next-generation archive storage technology. On Demand Start Date Tue, 12/05/2023 - 14:00

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Drug Discovery World

APRIL 6, 2023

These topics will be represented across a range of session types, including methods workshops, minisymposia, poster and plenary sessions, as well as keynotes, awards and lectures.

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Drug Discovery World

JUNE 7, 2023

That’s why at Macomics we have developed the ENIGMAC discovery platform, which allows stringent bioinformatic analysis coupled with macrophage gene editing technology; our platform enables strong target validation and drug screening using biologically relevant functional assays.

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Drug Discovery World

OCTOBER 3, 2022

He holds a PhD in Medicine from Leiden University, and an MSc in Bioinformatics and Artificial Intelligence from Brunel University. He has over 12 years of experience in the healthcare sector and is the author of over 30 peer- reviewed scientific articles. Fellowship Programme.

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Drug Discovery World

JULY 11, 2023

As a result, the company built a comprehensive understanding of their cells’ transcriptional and genomic landscape from that deep dataset, including insights into changes that could potentially limit the engineered cell’s stability and productivity.

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The Pharma Data

NOVEMBER 25, 2020

Egle has leveraged its unique bioinformatic and translational capabilities to successfully identify targets that will now be pursued under the terms of the alliance. Upon achievement of the target identification, Egle will receive an R&D milestone payment and investment from Takeda.

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The Pharma Data

MARCH 20, 2021

In connection with research programs covering yeast fermentation, fungal fermentation, lactic acid fermentation, bio catalysis and genomic tools including bioinformatics, the center is always on the lookout for the latest developments in inline measurement technology. Scope of possible application .

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Broad Institute

AUGUST 29, 2016

Software Engineering Broad scientists generate 24TB of raw genomic sequence data every day. Computational Biology Broad computational biologists and bioinformatics analysts collaborate with interdisciplinary teams of scientists who are working together to revolutionize the way biomedical research is done.

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Broad Institute

FEBRUARY 21, 2024

By Claire Hendershot February 21, 2024 Credit: Allison Colorado, Broad Communications Khalid Shakir is a principal software engineer in the McCarroll Lab. Now, Shakir has traded in his Commodore 64 for large-scale computational tools that he develops as a software engineer at the Broad Institute of MIT and Harvard.

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The Pharma Data

JANUARY 21, 2021

“Finalists are the top young scientists and engineers in the United States who will someday solve some of the world’s most vexing problems. Our most significant philanthropic commitments are in the area of science education, including the Regeneron Science Talent Search and Regeneron International Science and Engineering Fair.

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Drug Discovery World

JULY 26, 2023

This leap in understanding, which has been facilitated by the emergence of next generation sequencing (NGS) technologies and bioinformatics tools such as artificial intelligence (AI), has brought forward a new wave of precision medicine resources, diagnostics, and therapeutics specifically aiming to leverage the microbiome.

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The Pharma Data

SEPTEMBER 11, 2021

This precise and rational approach to library fabrication combined with sophisticated bioinformatics and software expertise expedites antibody discovery by decreasing risk, increasing speed, and lowering the failure rate for antibody therapeutic development. About Twist Bioscience Corporation. About Twist Bioscience Corporation.

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Drug Discovery World

NOVEMBER 8, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. from engineered peptide and antibody libraries’. Harriman will present ‘Discovering functional modulators of the ion channel Kv1.3

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Drug Discovery World

NOVEMBER 13, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Ali Madani, PhD, Founder and CEO, Profluent Bio, on: ‘Protein engineering with large language models’.

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Drug Discovery World

NOVEMBER 9, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Croasdale-Wood will then participate in a keynote chat, interviewed by Miho.

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Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

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Drug Discovery World

AUGUST 7, 2024

Billions of dollars are being invested in AI-driven techbios and in an industry where nothing changes overnight; even large biopharma companies are touting AI as key to how they’re transforming their discovery engines. Although this trend has already started, AI applications can rapidly accelerate it.

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Codon

AUGUST 28, 2024

And finally, people intent on causing harm could engineer pathogens to become more dangerous. But DNA screening tools can't simply flag any sequence that is similar to a potentially dangerous virus because the public databases also include engineered sequences comprising DNA sequences created from multiple different organisms.

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The Pharma Data

JULY 27, 2021

“Over the last five years, Teneobio developed leading-edge expertise in efficiently engineering differentiated multispecific and bispecific therapeutics for numerous indications with potentially better safety, efficacy and pharmacokinetic profiles than the first generation of T-cell engagers. chief executive officer of Teneobio.

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Drug Discovery World

NOVEMBER 4, 2022

Exscientia’s engineers are building proprietary automation hardware to enable high-throughput antibody profiling to support its predictive model building for multi-parameter optimisation. . Bioinformatics 2021 . Official comments . References . Abanades et al.

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Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

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Drug Target Review

DECEMBER 13, 2023

About the author Dr Sayoni Das SVP Bioinformatics at PrecisionLife Sayoni leads the research and development of bioinformatics pipelines that generate biological insights from PrecisionLife’s core technology and support drug discovery programmes.

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Drug Discovery World

NOVEMBER 15, 2022

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. Synthetic libraries for antibody drug discovery .

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Elrig

APRIL 29, 2024

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. Bioinformatics is all about bringing together different areas of knowledge. Do you think the current talent pool supply meets the demand?

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Drug Discovery World

SEPTEMBER 7, 2022

Let’s take a relatively simple example: with antibody engineering, you might start with an antibody, its target, and its binding affinity. Rather than analysing data, your data science or bioinformatics team will be spending their time linking, reconciling, and cleaning data. R&D data is highly complex .

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Drug Discovery World

NOVEMBER 30, 2023

Sphere Fluidics presence on the exhibition floor was bolstered by a presentation from Richard Hammond: ‘Picodroplets for cell Line engineering: A novel automation approach’. It was presented by Xiaole Shirley Liu, PhD, CEO, GV20 Therapeutics, and titled: ‘AI-based target and antibody discovery from patient tumour profiles’.

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Drug Discovery World

FEBRUARY 21, 2023

Ashwin Pillai is Test Engineer 3 in HTS & Assay Development at Ginkgo Bioworks, a company whose mission is to make biology easier to engineer. He also completed a Bioinformatics Certificate from Harvard Extension School.

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Drug Target Review

APRIL 5, 2024

Finally, comprehensive genetic knowledge also facilitates the use of powerful bioinformatic tools that strengthen the cell-line development process, especially for enhanced protein expression or monoclonality assessment.

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The Open Targets Blog

APRIL 25, 2023

Although the estate was undoubtedly pretty, the Hall had seen better days and was rather dominated by a 1950s building that provided laboratories for the light engineering company that had owned the site. ranging from university academics through engineers and clerical staff to the military. The same went for analysis tools.

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Codon

MAY 15, 2023

link ) *New base editors can engineer both mitochondrial and nuclear DNA. link ) *Hypoimmune pluripotent cells were engineered and then used for rejection-free transplantation in primates. link ) Engineered Pseudomonas microbes — which eat plant biomass — make isoprenol, a precursor to aviation fuels, with a 3.5

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Codon

MAY 15, 2023

link ) *New base editors can engineer both mitochondrial and nuclear DNA. link ) *Hypoimmune pluripotent cells were engineered and then used for rejection-free transplantation in primates. link ) Engineered Pseudomonas microbes — which eat plant biomass — make isoprenol, a precursor to aviation fuels, with a 3.5

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Vial

DECEMBER 5, 2023

Improvements in bioinformatics, robotics, liquid handling, and nucleic acid preparation will continue to transform NGS sequencing methods. We are more than just a CRO — we are “doers” — innovators, engineers, and ClinOps leaders. Conclusion NGS has tremendous potential for advancement and application in clinical research.

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Dark Matter Blog

AUGUST 31, 2020

The initial discussions that would lead to the PEARL-seq platform involved scanning the literature for the wings, propellers, and engines that we thought we could use. Finally, if we found an rSM that had biological activity, could we correlate that activity with the ability of the rSM to bind RNA?

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DrugBaron

NOVEMBER 22, 2022

For example, thrombin is generated by the cleavage of prothrombin by the prothrombinase complex; C3b the “engine” of the complement response is generated by the cleavage of C3 by enzymes such as complement factor B. Yet most modern proteomic protocols cannot readily distinguish thrombin from prothrombin or C3b from C3.

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Broad Institute

AUGUST 11, 2022

It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.”

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Drug Discovery World

OCTOBER 17, 2022

Data lakes served this same purpose, but while the idea was good, the results of search engines were often disappointing. Previously he held positions at LION Bioscience as a Scientific Bioinformatics Consultant before joining TIBCO Spotfire followed by ZephyrHealth.

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