Bioinformatics Engineering RNA 
Dark Matter Blog
AUGUST 31, 2020
Our overall mission at Arrakis is to expand the set of “druggable” targets for small-molecule medicines to include RNA. Today, we are pleased to announce that our article describing one such platform: “ PEARL-seq, A Photoaffinity Platform for the Analysis of Small Molecule-RNA Interactions ” was published in ACS Chemical Biology.
Elrig
APRIL 29, 2024
With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. She has played a key role inbuilding the target identification platform and a proprietary database of transcriptome-wide, functional RNA structures.
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Vial
DECEMBER 5, 2023
Transforming Genomics Research Next-generation sequencing (NGS) enables comprehensive genome sequencing and has transformed genomics research, offering vastly improved capabilities for analyzing DNA and RNA in a high-throughput and cost-effective manner. Satam et al. Let’s Connect.
Codon
MAY 15, 2023
Made from a Cas9 nickase (the histidine at amino acid position 840 is swapped for an alanine) fused to a reverse transcriptase enzyme (which makes DNA from RNA; transcription in reverse), prime editing clinical trials are expected to begin by 2025. link ) *New base editors can engineer both mitochondrial and nuclear DNA. EMBO Reports.
Codon
MAY 15, 2023
Made from a Cas9 nickase (the histidine at amino acid position 840 is swapped for an alanine) fused to a reverse transcriptase enzyme (which makes DNA from RNA; transcription in reverse), prime editing clinical trials are expected to begin by 2025. link ) *New base editors can engineer both mitochondrial and nuclear DNA. EMBO Reports.
Broad Institute
AUGUST 11, 2022
It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.” Most known bacterial defense systems work by sensing viral DNA or RNA, or cellular stress due to the infection. The finding was striking and unprecedented.
Codon
AUGUST 28, 2024
And finally, people intent on causing harm could engineer pathogens to become more dangerous. But DNA screening tools can't simply flag any sequence that is similar to a potentially dangerous virus because the public databases also include engineered sequences comprising DNA sequences created from multiple different organisms.
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