Codon

AUGUST 28, 2024

And finally, people intent on causing harm could engineer pathogens to become more dangerous. But DNA screening tools can't simply flag any sequence that is similar to a potentially dangerous virus because the public databases also include engineered sequences comprising DNA sequences created from multiple different organisms.

DNA 85

DNA Bioinformatics Virus Government 85

Elrig

APRIL 29, 2024

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. She has played a key role inbuilding the target identification platform and a proprietary database of transcriptome-wide, functional RNA structures.

Bioinformatics 59

Bioinformatics Molecular Biology Drugs Cell Based Assays 59

Drug Discovery World

NOVEMBER 30, 2023

Sphere Fluidics presence on the exhibition floor was bolstered by a presentation from Richard Hammond: ‘Picodroplets for cell Line engineering: A novel automation approach’. It was presented by Xiaole Shirley Liu, PhD, CEO, GV20 Therapeutics, and titled: ‘AI-based target and antibody discovery from patient tumour profiles’.

Protein Expression 147

Protein Expression Engineering DNA Therapies 147

Vial

DECEMBER 5, 2023

Transforming Genomics Research Next-generation sequencing (NGS) enables comprehensive genome sequencing and has transformed genomics research, offering vastly improved capabilities for analyzing DNA and RNA in a high-throughput and cost-effective manner. Satam et al. Let’s Connect.

Clinical Trials 52

Clinical Trials Trials RNA Bioinformatics 52

Codon

MAY 15, 2023

Made from a Cas9 nickase (the histidine at amino acid position 840 is swapped for an alanine) fused to a reverse transcriptase enzyme (which makes DNA from RNA; transcription in reverse), prime editing clinical trials are expected to begin by 2025. link ) *New base editors can engineer both mitochondrial and nuclear DNA. EMBO Reports.

DNA 52

DNA Bioinformatics Engineering Virus 52

Codon

MAY 15, 2023

Made from a Cas9 nickase (the histidine at amino acid position 840 is swapped for an alanine) fused to a reverse transcriptase enzyme (which makes DNA from RNA; transcription in reverse), prime editing clinical trials are expected to begin by 2025. link ) *New base editors can engineer both mitochondrial and nuclear DNA. EMBO Reports.

DNA 52

DNA Bioinformatics Engineering Virus 52

Broad Institute

AUGUST 11, 2022

It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.” Most known bacterial defense systems work by sensing viral DNA or RNA, or cellular stress due to the infection. The finding was striking and unprecedented.

DNA 52

DNA Virus Immune Response Bioinformatics 52

Codon

AUGUST 10, 2023

Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. ” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M.

DNA 93

DNA Cell Biology Molecular Biology Engineering 93

Codon

AUGUST 10, 2023

Engineered biology has profound potential to change how we live, but the field has become broad, bloated, nebulous. ” Foundations Basics of Synthetic Biology →Foundations for engineering biology , by Endy D. Journal of Biological Engineering (2010). → means “start here.” Nature (2005).

DNA 52

DNA Cell Biology Engineering Molecular Biology 52

Codon

APRIL 16, 2023

Codon Digest is my weekly roundup of research, news, and industry highlights about engineered biology. These microbes were engineered to express tumor antigens that could “elicit T cells that were licensed by the commensal immune program but specific for a tumor,” including both CD4+ and CD8+ T cells, according to the study.

Engineering 52

Engineering DNA RNA Science 52