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Advancing vaccine design: potential of peptide mimicry

Drug Target Review

In a new development, a recent paper published in Biology Methods & Protocols by Oxford University Press has highlighted a promising avenue for enhancing vaccine efficacy against infectious pathogens like the COVID-19 virus. The role of extracellular vesicles in COVID-19 virus infection [Internet].

Vaccine 98
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Finding the right CDMO partner for cell line development

Drug Target Review

Finally, comprehensive genetic knowledge also facilitates the use of powerful bioinformatic tools that strengthen the cell-line development process, especially for enhanced protein expression or monoclonality assessment. The first concern is microbial contamination.

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Q&A: How Terra became a backbone of public health pathogen surveillance

Broad Institute

As it turned out, software engineering teams at the Broad Institute had already created a solution — Terra , an open, secure, and collaborative environment created in a collaboration between Broad, Verily, and Microsoft, where users can analyze and share biomedical and public health data.

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Scientists discover new antiviral defense system in bacteria

Broad Institute

It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.” These bacterial proteins were instead directly sensing key parts of the virus. The cells underwent a dramatic defensive response and survived.

DNA 52
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Not all neoantigens are created equal

Drug Target Review

Recent advances in bioinformatics show clonal neoantigens are the best targets for immunotherapy, as I will elucidate below. Using powerful bioinformatics technology developed and validated with sequence data from the TRACERx study, researchers are able to identify clonal neoantigens from a patient’s unique tumour profile.

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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

link ) *New base editors can engineer both mitochondrial and nuclear DNA. link ) *Hypoimmune pluripotent cells were engineered and then used for rejection-free transplantation in primates. link ) Engineered Pseudomonas microbes — which eat plant biomass — make isoprenol, a precursor to aviation fuels, with a 3.5

DNA 52
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Monkey Embryos Grow to 25 Days — No Womb Required

Codon

link ) *New base editors can engineer both mitochondrial and nuclear DNA. link ) *Hypoimmune pluripotent cells were engineered and then used for rejection-free transplantation in primates. link ) Engineered Pseudomonas microbes — which eat plant biomass — make isoprenol, a precursor to aviation fuels, with a 3.5

DNA 52