Remove Bioinformatics Remove Immune Response Remove Vaccine
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Advancing vaccine design: potential of peptide mimicry

Drug Target Review

In a new development, a recent paper published in Biology Methods & Protocols by Oxford University Press has highlighted a promising avenue for enhancing vaccine efficacy against infectious pathogens like the COVID-19 virus. The implications of this finding are far-reaching, as it holds the potential to revolutionize vaccine design.

Vaccine 98
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A chance to design better vaccines?

SCIENMAG: Medicine & Health

A new paper in Biology Methods & Protocols, published by Oxford University Press, shows it may be possible to design vaccines that will induce a stronger immune response to infecting pathogens, such as the virus causing COVID-19.

Vaccine 60
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Not all neoantigens are created equal

Drug Target Review

These neoantigens are identified by T cells of the immune system as foreign proteins and thus trigger an immune response. Recent advances in bioinformatics show clonal neoantigens are the best targets for immunotherapy, as I will elucidate below. Neoantigens are recognised as non-self and trigger an immune response.

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Transforming cancer treatment for greatest impact

Drug Target Review

The preclinical results demonstrated significant immune responses and tumour regression. Could you elaborate on the mechanisms by which these responses are initiated within cancer cells? This induced anti-tumour immunity is also detectable by increased innate and adaptive immune cells in the tumour, spleen and blood.

Treatment 105
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Can Global Genomic Surveillance Forecast the Next Pandemic?

PLOS: DNA Science

Had we grown complacent in a world freed from a list of once-deadly infectious diseases, thanks largely to vaccines and other public health measures? Work on vaccines ensued too. • identifies parts of the virus to target to provoke an immune response from a vaccine. COVID clearly caught us off guard.

Virus 98
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Defense-Forward Biosecurity

Codon

For example, many different filoviruses attack white blood cells and cause similar innate immune responses , which makes it difficult to identify a particular species from only their DNA. New Yorkers wait to receive a monkeypox vaccine. When an anomaly is detected, a technician comes to remove the filter and analyze the data.

DNA 81
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Codon Digest: GPT-4 Controls a Robot

Codon

Skin microbes can trigger strong immune responses. These microbes were engineered to express tumor antigens that could “elicit T cells that were licensed by the commensal immune program but specific for a tumor,” including both CD4+ and CD8+ T cells, according to the study. BMC Bioinformatics. McCafferty C.L.