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Key industry partnerships advancing drug discovery

Drug Discovery World

Otsuka Pharmaceutical and Ionis Pharmaceuticals Otsuka Pharmaceutical and RNA therapy company Ionis have entered into a licence agreement for Otsuka to acquire exclusive marketing rights to Ionis’ hereditary angioedema (HAE) drug candidate donidalorsen in Europe.

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Leveraging ADCs in precision oncology strategy

Drug Target Review

By identifying proteins that only interact with each other in cancer, but not normal tissues, we can really expand the repertoire of ADC therapeutics beyond monoclonal antibodies developed based solely on RNA expression profiles. His work has been published in many high-impact journals and presented at international oncology meetings.

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The use-case for NGS

Drug Discovery World

DDW Editor Reece Armstrong speaks to Dr Darrell Green , Lecturer in RNA Biology Biomedical Research Centre Norwich Medical School University of East Anglia, about his work using next generation sequencing (NGS) and the areas the technology is impacting within drug discovery and development.

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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine. She has played a key role inbuilding the target identification platform and a proprietary database of transcriptome-wide, functional RNA structures.

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Synthetic biology tools advancing and accelerating drug discovery efforts

Drug Discovery World

As such, the synthesis of DNA oligonucleotides for routine molecular biology applications is often outsourced to service provider companies that operate DNA synthesisers to meet these demands. . It’s now possible to programme cell-free systems to make RNA and proteins that interact with each other,” Dr Laohakunakorn continues.

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The Codon Guide to Synthetic Biology

Codon

Journal of Molecular Biology (1961). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors. Link Molecular Cloning Techniques , by AddGene. Molecular Biology of the Cell, 4th Edition. . & Xie X.S. Nature (2011).

DNA 93
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The Codon Guide to Synthetic Biology

Codon

Journal of Molecular Biology (1961). Link (Golden Gate assembly) Other Basic Methods & Cloning →Basic Methods in Cellular and Molecular Biology , by multiple authors. Link Molecular Cloning Techniques , by AddGene. Molecular Biology of the Cell, 4th Edition. Molecular Systems Biology (2008).

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