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Biological Characterization of One Oxadiazole Derivative (5(4‐Hydroxyphenyl)‐2‐(N‐Phenyl Amino)‐1,3,4‐Oxadiazole): In Vitro, In Silico, and Network Pharmacological Approaches

Chemical Biology and Drug Design

5(4-Hydroxyphenyl)-2-(N-Phenyl amino)-1,3,4-Oxadiazole (Hppo) can considered as a versatile agent in designing novel pharmaceuticals. These results were confirmed by molecular modeling and bioinformatics tools. In the anticancer test, the compound showed strong anticancer activity in pancreatic cancer with apoptotic signaling pathways.

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Therapeutic Oligos 2025 Keynote Speakers Announced

Elrig

Prof Rory Johnson is an Associate Professor at University College Dublin, where his research focusses on uncovering the roles of long noncoding RNAs (lncRNAs) in human health and disease using an interdisciplinary combination of bioinformatic and experimental methods.

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Case study: Extracting tidy data from Open Targets Genetics with Otargen

The Open Targets Blog

Amir Feizi is the Director of Bioinformatics at OMass Therapeutics, a spinout from Professor Dame Carol Robinson’s Laboratory at the University of Oxford. Their work was recently published in Bioinformatics. We chat with him about otargen, and the importance of sharing open-source resources within the bioinformatics community.

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Unlocking the potential of natural products in drug discovery

Drug Target Review

In short, this hypothesis underscores the potential benefits of aligning pharmaceutical development more closely with nature. He was an early employee of Recursion Pharmaceuticals, where he scaled their high-content imaging platform by multiple orders of magnitude before joining Enveda in 2021. References Newman DJ, Cragg GM.

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AI At The Frontier: Empowering Early Career Professionals In Drug Discovery

Elrig

Harini Srinivasan is a Principal Scientific Associate at Serna Bio with over 10 years of research experience in academic institutions, health care organizations and pharmaceutical companies. With a background in Bioinformatics and Computational Biology, she has a keen interest in using technology to solve problems in healthcare and medicine.

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Finding the right CDMO partner for cell line development

Drug Target Review

Finally, comprehensive genetic knowledge also facilitates the use of powerful bioinformatic tools that strengthen the cell-line development process, especially for enhanced protein expression or monoclonality assessment.

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Egle Therapeutics Identifies First Novel Regulatory T-cell Targets in Research Alliance with Takeda

The Pharma Data

Egle has leveraged its unique bioinformatic and translational capabilities to successfully identify targets that will now be pursued under the terms of the alliance.