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This second ELRIG meeting on Therapeutic Oligonucleotides brings together esteemed scientists from academia, industry, and other members of the drug discovery community to explore the discovery, validation, and targeting of oligonucleotide-based drug candidates, including antisense oligonucleotides (ASOs) and small interfering RNA (siRNA).
The prognostic value of long noncoding RNA (lncRNA) LINC00460 has been reported in cervical cancer. In present study, LINC00460 was screened out through bioinformatics analysis. Abstract The acquired resistance of cancer to cisplatin (DDP) limits the efficacy of chemotherapy.
Through phylogenetic analysis and microscopy techniques, they identified a nuclear-encoded apicoplast RNA polymerase σ subunit called ApSigma. The initial subject of my research carrier was RNA polymerase principal sigma factors in bacteria. The first identification was based on a bioinformatic analysis.
With a background in biochemistry and bioinformatics, Lucy was interested in exploring how bioinformatics was applied to real-world healthcare data. I just graduated with a degree in Bioinformatics, and I was interested to see how the skills I learned could be applied. Was there anything surprising about your results?
When doctors sequenced the DNA and RNA found in Alice’s blood and synovial fluid—the liquid that surrounds and lubricates joints—they found abnormally low levels of genes encoding iron-storing proteins and high levels of epidermal growth factor receptor RNA. At least nine laboratories outside the U.S.
By identifying proteins that only interact with each other in cancer, but not normal tissues, we can really expand the repertoire of ADC therapeutics beyond monoclonal antibodies developed based solely on RNA expression profiles. His work has been published in many high-impact journals and presented at international oncology meetings.
presented the. Bioinformatics in the Faculty. Biogazelle, an innovative bioanalytical services company offering RNA and. study RNA virus replication and virus-host interactions and in particular the use of single-cell proteomics to aid in this research. In his webinar, Neil discussed the use of the MANTIS.
What other data have you collected from these samples (especially RNA-seq/scRNA-seq) Share any images you have of your samples H&E, immunofluorescence, ISH. A comment on your comfort level with bioinformatics, images, and custom analysis. If you don’t have any of your samples, a literature example can still be very helpful.
ABSTRACT Luteolin and quercetin, which are flavonoids, are present in various traditional Chinese medicines. Differentially expressed genes (DEGs) involved in luteolin and quercetin action that regulate adipogenic differentiation were identified using RNA sequencing (RNA-seq).
This was no small feat, because moths respond to a complex mixture of two or three different molecules that must be present at specific ratios. BMC Bioinformatics. Read An RNA-based system to study hepatitis B virus replication and evaluate antivirals. Comparison of transformations for single-cell RNA-seq data.
Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Link The Systems Biology Graphical Notation , by Le Novère N. Nature Biotechnology (2009). Link Subscribe to get future posts.
Technologies DNA Sequencing →DNA sequencing at 40: past, present and future , by Shendure J. Link A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , by Jinek M. Link In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation , by Jewett M.C. Nature (2017).
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